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Zaptra 25 Capsule

Paroxetine (25mg) + Clonazepam (0.5mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹313

Zaptra 25 Capsule is used for this medicine is used in the treatment of depression, anxiety, obsessive compulsive disorder, nerve pain, migraine prevention, insomnia, panic disorder, seizures and muscle spasm.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Paroxetine (25mg) + Clonazepam (0.5mg)
Available variants: capsule 25mg + 0.5mg 15`S
Best price: ₹313 (₹20.84 per capsule)
MRP: ₹329
Prescription: Required
Manufacturer: Intas Pharmaceuticals Ltd

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Zaptra 25 Capsule

Zaptra 25 Capsule contains Paroxetine (25mg) + Clonazepam (0.5mg). It belongs to the Antidepressant and Benzodiazepine / sedative-hypnotic class of medicines.

Uses of Zaptra 25 Capsule

  • This medicine is used in the treatment of depression
  • anxiety
  • obsessive compulsive disorder
  • nerve pain
  • migraine prevention
  • insomnia
  • panic disorder
  • seizures and muscle spasm.

Key benefits

  • Effective for depression and anxiety disorders
  • Also relieves nerve pain and prevents migraine
  • Usually taken once a day
  • Rapid relief of severe anxiety
  • Short-term help with sleep
  • Controls acute seizures

How Zaptra 25 Capsule works

Zaptra 25 Tablet is a combination of two medicines:.

How to take Zaptra 25 Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zaptra 25 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. It can cause deep unconsciousness and dangerously slow breathing, particularly with alcohol or an opioid. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zaptra 25 Capsule

Most side effects of Zaptra are mild and settle as the body adjusts. Reported side effects include:

  • Nausea
  • Dry mouth
  • Drowsiness or difficulty sleeping
  • Headache
  • Weight change
  • Reduced sexual desire
  • Constipation
  • Drowsiness
  • Dizziness
  • Unsteadiness
  • Poor concentration
  • Memory lapses

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zaptra 25 Capsule

PregnancyZaptra 25 Tablet is highly unsafe to use during pregnancy. Seek your doctors advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
BreastfeedingZaptra 25 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
AlcoholIt is unsafe to consume alcohol with Zaptra 25 Tablet .
DrivingDo not drive or operate machinery while taking this medicine.
KidneyZaptra 25 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Zaptra 25 Tablet may not be needed in these patients. Please consult your doctor.Use of Zaptra 25 Tablet can cause excessive sleepiness in patients with end stage kidney disease.
LiverZaptra 25 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zaptra 25 Tablet may be needed. Please consult your doctor.
Habit formingYes

Warnings and precautions

These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle. These medicines cause dependence. They are intended for the shortest possible course — usually two to four weeks — and are not a long-term treatment for anxiety or sleeplessness. Never stop a regular course suddenly. Withdrawal can cause severe anxiety, tremor and fits. Your doctor will taper it slowly. Do not drive or operate machinery. Drowsiness and slowed reactions can continue into the next day. Never combine with alcohol or with opioid painkillers — together they can stop your breathing. Older people are far more likely to fall, become confused or have memory problems on these medicines. Several of these are Schedule H1 medicines and must be dispensed against a prescription and entered in the pharmacy register.

Do not take Zaptra if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one. Not for people with severe breathing problems, sleep apnoea, or severe liver disease. Not for anyone with a history of dependence, except under specialist supervision.

Interactions with other medicines

Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group. Alcohol, opioids, antihistamines, muscle relaxants and other sedatives all deepen the sedation, sometimes fatally.

How to store Zaptra 25 Capsule

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Zaptra 25 Capsule

Give it a fair trial of several weeks, and keep your review appointments. Take it at the same time each day — at night if it makes you drowsy, in the morning if it disturbs sleep. Talking therapy alongside medicine works better than either alone for most people. Use it for the shortest course, and ask your doctor about talking therapy and sleep routine, which work without dependence. Take it only at bedtime if it is for sleep, and allow a full night before driving. Never share these medicines, and keep them secured.

Manufacturer and class

Manufacturer:
Intas Pharmaceuticals Ltd
Marketed by:
INTAS PHARMACEUTICALS`
Therapeutic class:
prescription
Drug class:
Antidepressant and Benzodiazepine / sedative-hypnotic

Substitutes for Zaptra 25 Capsule

Medicines with the same active ingredient (Paroxetine (25mg) + Clonazepam (0.5mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Zaptra 25 Capsule
Clonotril P 25 mg TabletTorrent Pharmaceuticals Ltdtablet · 15`S₹28011% cheaper
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Zaptra 25 Capsule FAQs

What is Zaptra 25 Capsule used for?
Zaptra 25 Capsule is commonly used for This medicine is used in the treatment of depression, anxiety, obsessive compulsive disorder, nerve pain, migraine prevention, insomnia, panic disorder, seizures and muscle spasm. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zaptra 25 Capsule?
Zaptra 25 Capsule contains Paroxetine (25mg) + Clonazepam (0.5mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zaptra 25 Capsule?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zaptra 25 Capsule work?
Zaptra 25 Tablet is a combination of two medicines:.
Is Zaptra 25 Capsule a prescription medicine?
Yes. Zaptra 25 Capsule is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zaptra 25 Capsule?
The side effects reported most often with Zaptra are Nausea, Dry mouth, Drowsiness or difficulty sleeping, Headache, Weight change. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zaptra 25 Capsule be taken during pregnancy?
Zaptra 25 Tablet is highly unsafe to use during pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zaptra.
Can I drink alcohol while taking Zaptra 25 Capsule?
It is unsafe to consume alcohol with Zaptra 25 Tablet .
What if I miss a dose of Zaptra 25 Capsule?
Take it as soon as you remember.
Is Zaptra 25 Capsule habit forming?
Yes Take Zaptra only as directed and for the duration your doctor advises.
Is there a cheaper substitute for Zaptra 25 Capsule?
Clonotril P 25 mg Tablet has the same active ingredient and strength and is listed from ₹280 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Zaptra 25 Capsule cost on PingMeDoc Pharmacy?
Zaptra 25 Capsule starts at ₹313 (MRP ₹329) on PingMeDoc Pharmacy. Available in capsule 25mg + 0.5mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zaptra 25 Capsule?
Zaptra 25 Capsule is manufactured by Intas Pharmaceuticals Ltd. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zaptra 25 Capsule delivered?
Zaptra 25 Capsule is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Zaptra 25 Capsule, Quick facts

Salt
Paroxetine (25mg) + Clonazepam (0.5mg)
Form
capsule
Best price
₹313 (₹20.84 per capsule)
MRP
₹329
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Intas Pharmaceuticals Ltd
Manufacturer
Intas Pharmaceuticals Ltd
Marketed by
INTAS PHARMACEUTICALS`
Therapeutic class
prescription
Drug class
Antidepressant and Benzodiazepine / sedative-hypnotic
Habit forming
Yes
Variants
capsule 25mg + 0.5mg 15`S
Delivery
Standard across India

References

The information on Zaptra 25 Capsule is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Zaptra 25 Capsule.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.