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Prescription requiredIntas Pharmaceuticals LtdAntiemetic
Zonalta 8 mg Tablet
Endoxifen (8mg)
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Zonalta 8 mg Tablet is used for prevention and treatment of nausea and vomiting due to chemotherapy (CINV), radiotherapy (RINV), and postoperative nausea and vomiting (PONV).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: Endoxifen (8mg)
Available variants: tablet 8 mg 10`S
Best price: ₹935 (₹93.52 per tablet)
MRP: ₹984
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Zonalta 8 mg Tablet
Zonalta 8 mg Tablet contains Endoxifen (8mg). It belongs to the 5-HT3 receptor antagonist (serotonin antagonist) class of medicines.
Uses of Zonalta 8 mg Tablet
- Prevention and treatment of nausea and vomiting due to chemotherapy (CINV)
- radiotherapy (RINV)
- and postoperative nausea and vomiting (PONV)
Key benefits
- Prevents chemotherapy-induced nausea and vomiting
- Prevents radiotherapy-related nausea and vomiting
- Helps control postoperative nausea and vomiting
- Improves tolerance to cancer therapy
How Zonalta 8 mg Tablet works
Ondansetron is a selective 5-HT3 (serotonin) receptor antagonist. It blocks serotonin-mediated stimulation of vagal afferents in the gut and the chemoreceptor trigger zone in the brain, thereby reducing nausea and vomiting.
How to take Zonalta 8 mg Tablet
Take tablet by mouth exactly as prescribed. It may be taken with or without food; taking after food may reduce stomach upset. Typical use is before chemotherapy/radiotherapy or as directed for postoperative nausea; swallow with water.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
If you miss a dose of Zonalta 8mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
If you take too much
An overdose of this medicine may be harmful — seek medical advice immediately. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Zonalta 8 mg Tablet
Most side effects of Zonalta are mild and settle as the body adjusts. Reported side effects include:
- Headache
- constipation
- diarrhea
- dizziness
- fatigue
- flushing
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Zonalta 8 mg Tablet
| Pregnancy | Consult doctor (use only if clearly needed; generally considered low risk when prescribed) |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Use with caution (alcohol may worsen dizziness and drowsiness) |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney CONSULT YOUR DOCTOR |
| Liver | Liver CONSULT YOUR DOCTOR |
| Habit forming | No |
Warnings and precautions
Use with caution in patients with prolonged QT interval, heart rhythm disorders, electrolyte imbalance (low potassium/magnesium), heart failure, or severe liver impairment (dose adjustment may be needed). Seek urgent help for palpitations, fainting, severe dizziness, or signs of serotonin syndrome (agitation, sweating, tremor) especially if taken with serotonergic medicines. Not recommended with apomorphine (risk of severe hypotension and loss of consciousness).
Do not take Zonalta if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will confirm this medicine is suitable for you.
Interactions with other medicines
Apomorphine (contraindicated), other QT-prolonging drugs (e.g., amiodarone, sotalol, quinolones, macrolides, antipsychotics), serotonergic drugs (SSRIs/SNRIs, MAOIs, tramadol, linezolid) increased serotonin syndrome risk, CYP3A4 inducers (carbamazepine, phenytoin, rifampicin) may reduce effect
How to store Zonalta 8 mg Tablet
Store below 25°C in a dry place. Protect from moisture and light. Keep out of reach of children.
Expert advice for Zonalta 8 mg Tablet
Inform your doctor if you experience chest pain or a fast heartbeat after starting treatment with Zonalta 8mg Tablet. Avoid breastfeeding during treatment with this medicine and for three months after the last dose. Zonalta 8mg Tablet might cause menstrual irregularity or amenorrhea. Consult your doctor. Use contraception to avoid getting pregnant during treatment with this medicine since it may cause fetal harm.
Manufacturer and class
- Manufacturer:
- INTAS PHARMACEUTICALS`
- Therapeutic class:
- Antiemetic
- Drug class:
- 5-HT3 receptor antagonist (serotonin antagonist)
- Chemical class:
- Triphenylethylenes
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Zonalta 8 mg Tablet FAQs
What is Zonalta 8 mg Tablet used for?
Zonalta 8 mg Tablet is commonly used for Prevention and treatment of nausea and vomiting due to chemotherapy (CINV), radiotherapy (RINV), and postoperative nausea and vomiting (PONV). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zonalta 8 mg Tablet?
Zonalta 8 mg Tablet contains Endoxifen (8mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zonalta 8 mg Tablet?
Take tablet by mouth exactly as prescribed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zonalta 8 mg Tablet work?
Ondansetron is a selective 5-HT3 (serotonin) receptor antagonist.
Is Zonalta 8 mg Tablet a prescription medicine?
Yes. Zonalta 8 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zonalta 8 mg Tablet?
The side effects reported most often with Zonalta are Headache, constipation, diarrhea, dizziness, fatigue. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zonalta 8 mg Tablet be taken during pregnancy?
Consult doctor (use only if clearly needed; generally considered low risk when prescribed) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zonalta.
Can I drink alcohol while taking Zonalta 8 mg Tablet?
Use with caution (alcohol may worsen dizziness and drowsiness)
What if I miss a dose of Zonalta 8 mg Tablet?
If you miss a dose of Zonalta 8mg Tablet, take it as soon as possible.
Is Zonalta 8 mg Tablet habit forming?
No. Zonalta 8 mg Tablet is not known to be habit forming when taken as prescribed.
How much does Zonalta 8 mg Tablet cost on PingMeDoc Pharmacy?
Zonalta 8 mg Tablet starts at ₹935 (MRP ₹984) on PingMeDoc Pharmacy. Available in tablet 8 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zonalta 8 mg Tablet?
Zonalta 8 mg Tablet is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zonalta 8 mg Tablet delivered?
Zonalta 8 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Zonalta 8 mg Tablet, Quick facts
- Salt
- Endoxifen (8mg)
- Form
- tablet
- Best price
- ₹935 (₹93.52 per tablet)
- MRP
- ₹984
- Prescription
- Required (Rx)
- Brand
- Intas Pharmaceuticals Ltd
- Manufacturer
- INTAS PHARMACEUTICALS`
- Therapeutic class
- Antiemetic
- Drug class
- 5-HT3 receptor antagonist (serotonin antagonist)
- Chemical class
- Triphenylethylenes
- Habit forming
- No
- Variants
- tablet 8 mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- Manufacturer labeling, established medical literature, standard pharmacology references
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Zonalta 8 mg Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.