

Injection · 500 mg · VIAL
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Amikacin 500 mg (as Amikacin sulfate) injection
Amicin 500 mg Injection Vial contains Amikacin 500 mg (as Amikacin sulfate) injection. Prescription required.
Monograph
Amicin 500 mg Injection Vial is a prescription medicine containing Amikacin 500 mg (as Amikacin sulfate) injection. Treatment of severe bacterial infections caused by susceptible organisms such as septicemia, hospital-acquired/ventilator-associated pneumonia, complicated urinary tract infections, intra-abdominal infections, skin/soft tissue infections, bone and joint infections; also used with other drugs for drug-resistant tuberculosis as per specialist advice. It belongs to the group of medicines called Aminoglycoside antibiotic.
For intravenous or intramuscular use only, to be administered by a healthcare professional. The dose and how long you take it depend on what you are being treated for and how you respond. Do not take more, or for longer, than your doctor has advised.
The side effects seen most often with Amicin 500 mg Injection Vial are injection site pain, nausea, vomiting and headache. Most are mild and settle as the body gets used to the medicine. Tell your doctor if one persists or worries you.
Before you start, tell your doctor about any liver, kidney or heart problem, whether you are pregnant, planning a pregnancy or breastfeeding, and every other medicine you take, including supplements and ayurvedic preparations. Some of them can change how Amicin 500 mg Injection Vial works.
Treatment of severe bacterial infections caused by susceptible organisms such as septicemia, hospital-acquired/ventilator-associated pneumonia, complicated urinary tract infections, intra-abdominal infections, skin/soft tissue infections, bone and joint infections; also used with other drugs for drug-resistant tuberculosis as per specialist advice
Most side effects of Amicin are mild and settle as the body gets used to the medicine. The ones reported most often are:
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
For intravenous or intramuscular use only, to be administered by a healthcare professional. Dose and duration depend on infection severity, body weight and kidney function; therapeutic drug monitoring may be needed. Maintain adequate hydration; do not self-inject.
Amikacin is an aminoglycoside antibiotic that binds to the 30S bacterial ribosomal subunit. It inhibits protein synthesis and causes misreading of mRNA, leading to bacterial cell death (bactericidal).
Prescription-only antibiotic. Risk of nephrotoxicity and ototoxicity—higher with prolonged therapy, high doses, dehydration, elderly, and kidney disease; monitor renal function and hearing. May cause neuromuscular blockade/respiratory depression, especially in myasthenia gravis or with anesthetics. Use only for susceptible bacterial infections; not effective for viral infections. Dose adjustment required in renal impairment.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Other nephrotoxic drugs (e.g., vancomycin, amphotericin B, cisplatin, cyclosporine/tacrolimus), loop diuretics (furosemide, ethacrynic acid) increase ototoxicity risk, other aminoglycosides, neuromuscular blockers and anesthetics (enhanced blockade), polymyxins, cephalosporins (additive kidney risk), NSAIDs may worsen renal function
Store below 25°C, protected from light. Do not freeze. Keep in original pack; use immediately after opening/reconstitution as per label and discard unused portion.
Amikacin 500 mg Injection (generic), Amikacin 500mg Inj (Cipla), Amikacin 500mg Inj (Alkem), Amikacin 500mg Inj (Sun Pharma), Amikacin 500mg Inj (Intas)
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
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Good to know
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance.
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