Amisant OD 400 Tablet

Amisant Od 400 Tablet contains Amisulpride (400mg). Prescription required.

Treatment of schizophrenia and related psychotic disorders (positive and negative symptoms); may also be used for acute psychosis and maintenance therapy as prescribed.

Amisulpride is an atypical antipsychotic that blocks dopamine D2/D3 receptors. At higher doses it reduces dopaminergic overactivity responsible for psychotic symptoms, helping improve thought disturbances, hallucinations and delusions.

Take by mouth exactly as prescribed, usually once daily (OD). Swallow the tablet whole with water; do not crush or chew. Can be taken with or without food; take at the same time each day and do not stop suddenly without medical advice.

Sleepiness, dizziness, insomnia, anxiety, constipation, nausea, dry mouth, weight gain, increased prolactin (breast tenderness/galactorrhoea, menstrual changes, sexual dysfunction), tremor, rigidity/extrapyramidal symptoms

Prescription-only antipsychotic. May cause drowsiness—avoid driving/operating machinery until you know the effect. Risk of QT prolongation/arrhythmias; use caution in heart disease, electrolyte imbalance, bradycardia, or with other QT-prolonging drugs. Can cause neuroleptic malignant syndrome (fever, rigidity, confusion)—seek urgent care. May cause tardive dyskinesia and extrapyramidal symptoms. Increases prolactin; caution in breast cancer or prolactin-dependent tumors. Use caution in elderly (especially dementia-related psychosis), liver/kidney impairment (dose adjustment in renal impairment), and seizure disorders. Monitor weight, glucose/lipids where appropriate.

Alcohol and other CNS depressants (increased sedation), QT-prolonging medicines (e.g., amiodarone, sotalol, quinidine, certain antibiotics like macrolides/fluoroquinolones, certain antifungals, tricyclics), other antipsychotics, levodopa/dopamine agonists (antagonistic effect), antihypertensives (additive hypotension), medicines causing low potassium/magnesium (e.g., diuretics) increasing QT risk, strong CYP interactions are less prominent but clinical monitoring advised.

Store below 25°C in a dry place, protected from moisture and direct light. Keep in original blister pack and out of reach of children.

Solian 400 Tablet, Amisulpride 400 Tablet (generic), Amisafe 400 Tablet, Amisure 400 Tablet, Amipride 400 Tablet