Amitrip 25MG

Amitriptyline (25mg)

Depression, neuropathic (nerve) pain, migraine/tension-type headache prevention, anxiety symptoms (as prescribed), insomnia associated with depression (off-label)

Amitriptyline is a tricyclic antidepressant that increases levels of serotonin and noradrenaline in the brain by inhibiting their reuptake. It also modulates pain pathways, which helps in chronic nerve pain and headache prevention.

Oral tablet. Take exactly as prescribed, usually once daily at bedtime (may cause drowsiness). Can be taken with or without food; take with food if stomach upset occurs. Do not stop suddenly—dose should be tapered on medical advice.

Drowsiness, dry mouth, constipation, dizziness, blurred vision, weight gain, nausea, headache, difficulty urinating, increased heart rate

May cause sedation and impair driving/operating machinery. Risk of suicidal thoughts in young adults, especially when starting or changing dose. Avoid abrupt discontinuation (withdrawal symptoms). Use with caution in heart disease/arrhythmias, recent heart attack, glaucoma, urinary retention/prostatic enlargement, seizures, bipolar disorder, liver disease, elderly (falls/confusion). Seek urgent care for severe mood changes, serotonin syndrome symptoms, or allergic reactions.

MAO inhibitors (contraindicated), other serotonergic drugs (SSRIs/SNRIs, tramadol, linezolid) increasing serotonin syndrome risk, CNS depressants (alcohol, benzodiazepines, opioids) causing excess sedation, anticholinergics causing increased side effects, QT-prolonging drugs (some antiarrhythmics/antipsychotics/macrolides), cimetidine (may increase levels), carbamazepine/phenytoin (may reduce levels), antihypertensives (may alter BP)

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Tryptomer 25 Tablet, Elavil 25 Tablet, Triptizol 25 Tablet, Amitone 25 Tablet, Amitriptyline 25 mg Tablet (generic)