Dapa Cad M 1000 Tab

Tablet

Type 2 diabetes mellitus (to improve glycaemic control as an adjunct to diet and exercise); may be used when dual therapy is required

Dapagliflozin (an SGLT2 inhibitor) lowers blood glucose by increasing urinary glucose excretion via the kidneys. Metformin reduces hepatic glucose production and improves insulin sensitivity, helping the body use insulin more effectively.

Oral tablet. Take exactly as prescribed. Usually taken once daily with food (preferably with/after the main meal) to reduce stomach upset; swallow whole if extended-release—do not crush or chew. Maintain adequate hydration.

Nausea, vomiting, diarrhoea, abdominal discomfort, loss of appetite, headache, increased urination, thirst, genital yeast infection, urinary tract infection, dizziness

Prescription-only antidiabetic. Risk of lactic acidosis with metformin (higher in kidney impairment, dehydration, heavy alcohol use, severe infection, shock, liver disease); kidney function should be assessed before and during therapy. Dapagliflozin may cause dehydration/low blood pressure, genital/urinary infections, and rarely ketoacidosis (can occur even with near-normal sugars)—seek urgent care for nausea, vomiting, abdominal pain, rapid breathing. Stop temporarily during acute illness, prolonged fasting, major surgery, or before iodinated contrast procedures as advised. Monitor for hypoglycaemia when used with insulin/sulfonylureas. Not for type 1 diabetes.

Insulin and sulfonylureas (increased hypoglycaemia risk), diuretics (increased dehydration/hypotension risk), ACE inhibitors/ARBs/NSAIDs (may affect renal function), iodinated contrast media (increases lactic acidosis risk—temporary stoppage may be needed), alcohol (raises lactic acidosis risk), cationic drugs affecting renal tubular secretion e.g., cimetidine (may increase metformin levels)

Store below 25°C in a dry place, protected from moisture and direct light. Keep in original blister pack and out of reach of children.

Xigduo XR 10/1000 Tablet, Dapamet XR 10/1000 Tablet, Dapaflo M XR 10/1000 Tablet, DapaMet 10/1000 Tablet, Dapamax M XR 10/1000 Tablet