Distributor inventory

Relief of bronchospasm in asthma and COPD (chronic bronchitis, emphysema); helps ease wheeze, chest tightness and shortness of breath.

Etophylline and theophylline are methylxanthine bronchodilators. They relax bronchial smooth muscles and improve airflow, and also reduce airway responsiveness by inhibiting phosphodiesterase and antagonizing adenosine.

Oral syrup. Take exactly as prescribed; measure with a dosing cup/spoon. Can be taken with food to reduce stomach upset; take at the same time each day and avoid exceeding the dose. Do not use for acute severe asthma attack unless advised by a doctor.

Nausea, vomiting, stomach pain/heartburn, headache, tremor, restlessness/insomnia, dizziness, palpitations, increased urination

Use with caution in heart disease/arrhythmias, hypertension, hyperthyroidism, seizure disorder, peptic ulcer, liver or kidney impairment, and in elderly. Overdose can cause severe vomiting, fast/irregular heartbeat and seizures—seek urgent care. Avoid excess caffeine. Dose adjustments may be needed in smokers, fever/viral illness, and liver disease. Not recommended for self-medication in children; use only on medical advice.

Macrolide antibiotics (erythromycin/clarithromycin), fluoroquinolones (ciprofloxacin), cimetidine, fluvoxamine and other CYP inhibitors may increase levels/toxicity; rifampicin, phenytoin, carbamazepine and smoking may decrease effect; beta-agonists and other stimulants/caffeine may increase palpitations; alcohol may increase side effects; lithium levels may decrease; may increase effects/levels of warfarin in some cases—monitor as advised.

Store below 25°C in a cool, dry place. Protect from light. Keep bottle tightly closed and out of reach of children.

Deriphyllin Syrup 100 ml, Deriphyllin BM Expectorant 100 ml, Deriphyllin Retard (tablets/capsules), Etofylline+Theophylline Syrup (generic)