Diamyk M2 Tab

Tablet

Type 2 diabetes mellitus (adult) to improve blood glucose control when diet and exercise alone are insufficient; used when combination therapy is required.

Glimepiride (a sulfonylurea) increases insulin release from pancreatic beta cells and improves glucose utilization. Metformin (a biguanide) reduces hepatic glucose production and improves insulin sensitivity, lowering blood glucose without causing significant hypoglycaemia when used alone.

Oral tablet. Take exactly as prescribed, usually once or twice daily with meals to reduce stomach upset. Swallow whole (do not crush/chew if SR/ER). Monitor blood sugar regularly and follow diet/exercise advice.

Nausea,diarrhoea,abdominal pain,loss of appetite,metallic taste,hypoglycaemia,dizziness,headache,weight gain

Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise, elderly, renal/hepatic impairment). Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, muscle pain, abdominal pain, or unusual sleepiness. Avoid in severe kidney disease; dose adjustment/monitoring required in renal impairment. Use caution in liver disease, heart failure, dehydration, and during severe infection or surgery. Temporarily stop metformin before/after iodinated contrast procedures as advised by doctor. Not for type 1 diabetes or diabetic ketoacidosis.

Alcohol (increases risk of hypoglycaemia/lactic acidosis),iodinated contrast media,insulin/other antidiabetics (additive hypoglycaemia),beta-blockers (mask hypoglycaemia symptoms),ACE inhibitors (may enhance glucose-lowering),diuretics and corticosteroids (may raise glucose),fluoroquinolones (glucose disturbances),azole antifungals/clarithromycin (may increase sulfonylurea effect),rifampicin (may reduce effect),NSAIDs and salicylates (may increase hypoglycaemia),cimetidine (may increase metformin levels)

Store below 25°C in a cool, dry place. Protect from moisture and direct sunlight. Keep in original blister pack and out of reach of children.

Amaryl M 2 Tablet,Glimepiride+Metformin 2 mg/500 mg SR Tablet (generic),Glimestar M2 Tablet,Glimy M2 Tablet,Diapride M2 Tablet