Esohap 40MG Tab 10S

Tablet

Gastroesophageal reflux disease (GERD) and heartburn, erosive esophagitis, gastric and duodenal ulcers, NSAID-induced ulcer prevention, Helicobacter pylori eradication (with antibiotics), Zollinger-Ellison syndrome/pathological hypersecretory conditions

Esomeprazole is a proton pump inhibitor (PPI) that irreversibly blocks the H+/K+ ATPase (proton pump) in gastric parietal cells. This reduces stomach acid production and allows ulcers/erosions in the esophagus and stomach to heal.

Tablet: take exactly as prescribed, usually once daily 30–60 minutes before food (preferably before breakfast). Swallow whole with water; do not crush or chew. Duration depends on the condition; for H. pylori, use only with the prescribed antibiotics regimen.

Headache, diarrhea, nausea, abdominal pain, constipation, flatulence, vomiting, dizziness

Use with caution in severe liver disease. Long-term use may increase risk of vitamin B12 deficiency, low magnesium, fractures (osteoporosis), and Clostridioides difficile-associated diarrhea. May rarely cause kidney inflammation (interstitial nephritis) or severe skin reactions; seek medical help if rash, reduced urination, or severe diarrhea occurs. PPIs can mask symptoms of gastric cancer—evaluate alarm features (weight loss, vomiting, bleeding, dysphagia).

Clopidogrel (reduced activation/effect), warfarin (INR changes), phenytoin, diazepam, digoxin (increased levels with hypomagnesemia), methotrexate (especially high dose), tacrolimus, ketoconazole/itraconazole/posaconazole (reduced absorption), atazanavir/nelfinavir (reduced levels—avoid), rifampicin and St John’s wort (reduced esomeprazole effect)

Store below 25°C in a dry place, protected from moisture and direct light. Keep in original blister pack and out of reach of children.

Nexium 40 Tablet, Sompraz 40 Tablet, Esomac 40 Tablet, Esoz 40 Tablet, Esoz-L 40 Tablet