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Tablet · 10`S
Before you take it
Use with caution (consult doctor)
Avoid (may increase side effects; nitroimidazoles can cause disulfiram-like reaction in some patients)
Monograph
Tablet
Treatment of mixed bacterial and protozoal infections, especially acute infectious diarrhoea, dysentery, gastroenteritis, and other gastrointestinal infections where both bacteria and amoebiasis/giardiasis are suspected
Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase/topoisomerase IV, stopping bacterial DNA replication. Ornidazole is a nitroimidazole that forms reactive metabolites in anaerobic/protozoal cells, damaging DNA and leading to cell death.
Take by mouth as prescribed by a doctor, usually after food to reduce stomach upset. Swallow whole with water; complete the full course even if symptoms improve. Avoid taking with antacids/iron/zinc/calcium supplements within 2 hours before or after the dose.
Nausea, vomiting, abdominal pain, diarrhoea, headache, dizziness, metallic taste, loss of appetite
Prescription-only medicine. Not recommended in pregnancy unless clearly needed; avoid breastfeeding or consult doctor. Use with caution in kidney or liver disease, epilepsy/seizure disorders, history of tendon disorders, and in elderly. Fluoroquinolones may cause tendonitis/tendon rupture, peripheral neuropathy, CNS effects, and QT prolongation; stop and seek medical help if tendon pain, numbness/tingling, severe dizziness, palpitations, rash, or severe diarrhoea occurs. Avoid excessive sunlight/UV exposure (photosensitivity risk). Not for viral diarrhoea; ensure hydration and medical evaluation if blood in stools, high fever, or dehydration.
Antacids containing magnesium/aluminium, sucralfate, iron/zinc/calcium supplements (reduce absorption), warfarin/other anticoagulants (bleeding risk), antiarrhythmics/QT-prolonging drugs (e.g., amiodarone, sotalol, macrolides, antipsychotics), corticosteroids (increased tendon rupture risk), NSAIDs (may increase seizure risk), antidiabetic drugs/insulin (blood sugar disturbances)
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Oflox OZ Tablet, Oflomac OZ Tablet, Zenflox OZ Tablet, O2 Tablet, Flox OZ Tablet
At a glance
Good to know
Treatment of mixed bacterial and protozoal infections, especially acute infectious diarrhoea, dysentery, gastroenteritis, and other gastrointestinal infections where both bacteria and amoebiasis/giardiasis are suspected
Nausea, vomiting, abdominal pain, diarrhoea, headache, dizziness, metallic taste, loss of appetite
Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase/topoisomerase IV, stopping bacterial DNA replication. Ornidazole is a nitroimidazole that forms reactive metabolites in anaerobic/protozoal cells, damaging DNA and leading to cell death.
Take by mouth as prescribed by a doctor, usually after food to reduce stomach upset. Swallow whole with water; complete the full course even if symptoms improve. Avoid taking with antacids/iron/zinc/calcium supplements within 2 hours before or after the dose.
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
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Brand
CELTIC PHARMA
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Manufacturer: CELTIC PHARMA
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: Manufacturer labeling, established medical literature (fluoroquinolones and nitroimidazoles), standard treatment guidelines for infectious diarrhoea
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