Gliben 2M Tab

Tablet

Treatment of type 2 diabetes mellitus in adults as an adjunct to diet and exercise; may be used alone or with other antidiabetic medicines (as prescribed).

Glimepiride is a sulfonylurea that lowers blood glucose mainly by stimulating insulin release from pancreatic beta cells. It may also improve peripheral insulin sensitivity, helping the body use glucose better.

Oral tablet. Take exactly as prescribed, usually once daily with breakfast or the first main meal. Swallow with water; do not skip meals to reduce risk of low blood sugar. Monitor blood glucose regularly.

hypoglycaemia (low blood sugar), dizziness, headache, nausea, stomach upset, diarrhoea, weight gain, skin rash

Risk of hypoglycaemia, especially with missed meals, excessive exercise, alcohol intake, elderly patients, or when used with other glucose-lowering drugs. Use with caution in kidney or liver impairment; dose adjustment may be needed. Avoid driving/operating machinery if experiencing hypoglycaemia symptoms. Tell your doctor if you have sulfonylurea allergy, G6PD deficiency (risk of haemolysis), or if you are fasting/ill. Not for type 1 diabetes or diabetic ketoacidosis. Seek urgent care for severe hypoglycaemia, jaundice, or severe allergic reactions.

Insulin and other antidiabetics (increased hypoglycaemia risk), beta-blockers (may mask hypoglycaemia), azole antifungals (e.g., fluconazole), macrolide antibiotics (e.g., clarithromycin), quinolones, NSAIDs, salicylates, warfarin (effect may change), corticosteroids (raise glucose), thiazide/loop diuretics (raise glucose), rifampicin (reduced effect), ACE inhibitors (may increase hypoglycaemia), alcohol (can increase hypoglycaemia)

Store below 25°C in a dry place, protected from light and moisture. Keep in original strip and out of reach of children.

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