Glicla Dm 80MG Tab

Tablet

Type 2 diabetes mellitus (non-insulin-dependent) to help control blood glucose, especially when diet and exercise alone are insufficient

Gliclazide is a sulfonylurea antidiabetic that stimulates the pancreas to release insulin by closing ATP-sensitive potassium channels in beta cells. This increases insulin secretion and helps lower blood glucose levels.

Take by mouth exactly as prescribed. Usually taken with/just before meals (often breakfast; if divided dose, with breakfast and dinner) to reduce risk of hypoglycaemia. Swallow tablet with water; do not skip meals.

Hypoglycaemia, dizziness, headache, nausea, stomach upset, diarrhoea, weight gain, skin rash/itching, elevated liver enzymes

May cause hypoglycaemia (higher risk with missed meals, excess exercise, alcohol, elderly, kidney/liver impairment). Use caution in renal or hepatic disease; dose adjustment/monitoring may be needed. Avoid driving/operating machinery if symptoms of low sugar occur. Inform doctor about fever, infection, surgery, or major stress (therapy may need change). Rare: severe skin reactions, blood dyscrasias, hepatitis/jaundice—seek medical help if rash, easy bruising, yellowing of eyes/skin, or persistent nausea occurs. Not for type 1 diabetes or diabetic ketoacidosis.

Other antidiabetics/insulin (increased hypoglycaemia), alcohol (disulfiram-like reaction and hypoglycaemia risk), fluconazole/miconazole (increased gliclazide effect), macrolides (e.g., clarithromycin), sulfonamides, warfarin (may alter anticoagulant effect), beta-blockers (mask hypoglycaemia symptoms), corticosteroids/thiazide diuretics/sympathomimetics (raise glucose), rifampicin (reduced effect)

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

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