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MRP, inclusive of all taxes
Delivered across India. ₹49 delivery, free above ₹999.
Pack: Tablet · 15 Tablet
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Contains: Glimepiride (1mg) + Metformin (500mg)
Glimibrit M 1 Tablet contains Glimepiride (1mg) + Metformin (500mg). Prescription required.
Glimibrit M 1 Tablet is a prescription medicine containing Glimepiride (1mg) + Metformin (500mg). It is used for type 2 diabetes mellitus in adults when diet, exercise alone are insufficient, useful when fasting and post-meal glucose are both elevated requiring dual therapy. It belongs to the group of medicines called Sulfonylurea and Biguanide.
Take Glimibrit M 1 Tablet with the first main meal of the day to reduce hypoglycaemia and GI upset; swallow whole with water; dose titration must be done by physician based on glucose readings. The dose and how long you take it depend on what you are being treated for and how you respond. Do not take more, or for longer, than your doctor has advised.
The side effects seen most often with Glimibrit M 1 Tablet are lactic acidosis (metformin), severe/prolonged hypoglycaemia, cholestatic jaundice and blood dyscrasias. Most are mild and settle as the body gets used to the medicine. Tell your doctor if one persists or worries you.
Before you start, tell your doctor about any liver, kidney or heart problem, whether you are pregnant, planning a pregnancy or breastfeeding, and every other medicine you take, including supplements and ayurvedic preparations. Some of them can change how Glimibrit M 1 Tablet works.
Most side effects of Glimibrit M are mild and settle as the body gets used to the medicine. The ones reported most often are:
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Take Glimibrit M 1 Tablet with the first main meal of the day to reduce hypoglycaemia and GI upset; swallow whole with water; dose titration must be done by physician based on glucose readings.
Glimepiride closes pancreatic β-cell ATP-sensitive K+ channels (SUR1/Kir6.2), causing depolarisation, Ca2+ influx and insulin release; metformin activates AMPK to reduce hepatic gluconeogenesis and improve peripheral insulin sensitivity.
Monitor renal function before and during therapy; stop and seek urgent care for rapid breathing, severe weakness, abdominal pain (lactic acidosis symptoms); counsel on hypoglycaemia recognition and carrying glucose; dose reduction needed in elderly or reduced renal function; avoid dehydration and prolonged fasting; use caution in G6PD deficiency (haemolysis risk with sulfonylureas).
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Store at 20–25°C (permitted 15–30°C) in a dry place, protected from moisture and direct light; keep in original blister.
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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance.
