Hynidase 2ML

Hyaluronidase Injection IP 1500 IU/2 mL (1500 IU vial with 2 mL diluent)

Adjunct to increase dispersion and absorption of injected drugs and fluids (hypodermoclysis), to facilitate subcutaneous/IM injections, and to promote reabsorption of excess fluids (e.g., edema, hematoma); also used as an adjunct in local anaesthesia (e.g., ophthalmic procedures) as per clinician.

Hyaluronidase is an enzyme that depolymerizes hyaluronic acid in connective tissue. This temporarily decreases the viscosity of the intercellular matrix and increases tissue permeability, enhancing spread and absorption of injected solutions.

For injection use only, administered by a healthcare professional. Given subcutaneously, intramuscularly, or locally mixed with/alongside compatible solutions as advised. Dose and technique depend on the procedure and clinical indication; follow physician instructions and do not self-administer.

Injection site pain, redness, swelling, itching, rash/urticaria, headache, nausea, dizziness, allergic reactions (rare), anaphylaxis (very rare)

Prescription-only; use only under medical supervision. Do not use in patients with known hypersensitivity to hyaluronidase or components. Use caution in areas of infection, inflammation, or malignancy (may increase spread). Not for intravenous use. Avoid use to enhance absorption of local anaesthetics in areas supplied by end arteries (risk of ischemia). Monitor for allergic reactions; keep emergency treatment available.

May increase systemic absorption and effects of co-administered injectable drugs (e.g., local anaesthetics, opioids, antibiotics). Concomitant use with high-dose salicylates, corticosteroids, antihistamines, estrogens may reduce hyaluronidase effect. Avoid mixing with incompatible solutions; follow compatibility guidance.

Store at 2–8°C, protect from light; do not freeze. Keep in original pack. Use immediately after reconstitution; discard any unused portion as per policy.

Hynidase Injection 1500 IU (other pack), Hyalase Injection 1500 IU, Hyaluronidase Injection IP 1500 IU (generic), Vitrase (hyaluronidase) injection, Hyaluronidase 1500 IU Injection (various brands)