Linabite M 5/500 Tablet

Linabite M 5/500 Tablet contains Linagliptin 5 mg + Metformin 500 mg (as Metformin Hydrochloride). Prescription required.

Treatment of type 2 diabetes mellitus to improve glycaemic control (along with diet and exercise), especially when metformin alone or linagliptin alone is insufficient

Linagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP), leading to increased insulin release and reduced glucagon in a glucose-dependent manner. Metformin decreases hepatic glucose production and improves peripheral insulin sensitivity, thereby lowering blood glucose.

Oral tablet; take exactly as prescribed. Usually taken with meals to reduce stomach upset; swallow whole with water. Do not crush/chew; follow dosing schedule advised by doctor and monitor blood glucose regularly.

Nausea, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, nasopharyngitis, cough, dizziness, hypoglycaemia (more likely with other antidiabetics), rash

Not for type 1 diabetes or diabetic ketoacidosis. Metformin can rarely cause lactic acidosis—risk increases with severe kidney disease, dehydration, sepsis, alcohol excess, liver disease, or hypoxia; assess renal function before and during therapy. Temporarily stop metformin around iodinated contrast procedures and major surgery as advised by doctor. Use caution in elderly and in patients with renal/hepatic impairment; seek care for severe abdominal pain (possible pancreatitis), persistent vomiting, rapid breathing, or unusual muscle pain/weakness.

Alcohol (increases lactic acidosis risk), iodinated contrast media, cationic drugs affecting renal tubular secretion (e.g., cimetidine), diuretics and ACE inhibitors (may affect renal function), corticosteroids and sympathomimetics (raise glucose), insulin/sulfonylureas (increase hypoglycaemia risk), rifampicin (may reduce linagliptin effect via P-gp/CYP induction)

Store below 25°C, protected from light and moisture. Keep in original blister pack and out of reach of children.

Trajenta Duo 5/500 Tablet, Jentadueto 2.5/500 Tablet, Lincora-M 5/500 Tablet, Linamet 5/500 Tablet, Linagliptin+Metformin 5/500 generic tablets