Otrivin Advance Adult Nasal Spray

Otrivin Advance Adult Nasal Spray contains Xylometazoline hydrochloride 0.1% w/v (1 mg/mL) nasal spray.

Relief of nasal congestion due to common cold, allergic rhinitis (hay fever), sinusitis; may help open blocked nose and improve breathing

Xylometazoline is an alpha-adrenergic agonist that constricts blood vessels in the nasal mucosa. This reduces swelling and mucus congestion, improving airflow through the nose.

For adults and adolescents ≥12 years: 1 spray in each nostril up to 2-3 times daily as needed. Use for a maximum of 3 consecutive days unless advised by a doctor. Blow nose before use; keep bottle upright and avoid sharing the spray.

Nasal dryness, burning or stinging in nose/throat, sneezing, irritation, headache, nausea, palpitations, rebound congestion (with overuse)

Do not use for more than 3 days (risk of rebound congestion/rhinitis medicamentosa). Use with caution in hypertension, heart disease, hyperthyroidism, diabetes, enlarged prostate, glaucoma. Avoid in atrophic rhinitis or after certain nasal surgeries unless prescribed. Seek medical advice if symptoms persist/worsen. Not recommended for children <12 years for this strength. Do not exceed recommended dose.

MAO inhibitors (or within 14 days), tricyclic antidepressants, other sympathomimetics/decongestants, certain antihypertensives (may reduce control of blood pressure)

Store below 25°C in a cool, dry place. Protect from light. Keep container tightly closed; keep out of reach of children.

Xylometazoline 0.1% Nasal Spray (generic), Nasivion Adult Nasal Spray (Oxymetazoline 0.05%), D-Cold Total Nasal Spray (varies by brand), Xylorin 0.1% Nasal Drops/Spray, Otrivin Adult Nasal Drops (Xylometazoline 0.1%)