Phenergan Syrup

Phenergan Syrup contains Promethazine hydrochloride 5 mg/5 mL. Prescription required.

Relief of allergic conditions such as allergic rhinitis (runny nose, sneezing), urticaria (hives), pruritus (itching), and other allergy-related symptoms; may also be used for nausea/vomiting and motion sickness when prescribed.

Promethazine is a first-generation H1 antihistamine. It blocks histamine H1 receptors to reduce allergy symptoms and also has anticholinergic and sedative effects which can help with nausea and motion sickness.

Oral syrup: take the dose exactly as prescribed by a doctor. Can be taken with or without food; taking after food may reduce stomach upset. Measure with a proper measuring cup/spoon. May cause drowsiness—prefer bedtime dosing if advised; do not drive or operate machinery after taking.

Drowsiness, dizziness, dry mouth, blurred vision, constipation, nausea, vomiting, confusion (especially in elderly), urinary retention

Schedule H: use only on prescription. Causes significant drowsiness—avoid driving, alcohol and other sedatives. Not recommended in children below 2 years (risk of severe respiratory depression); use with caution and only under medical advice in older children. Use caution in asthma/COPD, sleep apnoea, glaucoma, prostate enlargement/urinary retention, epilepsy, and liver disease. May cause photosensitivity. Seek urgent help for breathing difficulty, severe sedation, allergic reaction, or unusual movements.

Alcohol, opioids, benzodiazepines and other CNS depressants (increased sedation/respiratory depression); other anticholinergics (increased dry mouth/constipation/urinary retention); MAO inhibitors (enhanced anticholinergic/CNS effects); tricyclic antidepressants; antihypertensives (additive dizziness/low BP).

Store below 25°C, protected from light and moisture. Keep bottle tightly closed. Keep out of reach of children.

Promethazine Syrup (generic), Avomine Syrup, Procomil Syrup, Phensedyl (promethazine-containing variants as per formulation), Histazine Syrup (different antihistamine)