Rabeprazole 20 mg + Domperidone 30 mg (Sustained/Prolonged release)
Tablet
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Tablet · 10`S
Before you take it
Consult doctor (use with caution)
Use with caution; alcohol can worsen acidity/GERD symptoms
Monograph
Tablet
Gastroesophageal reflux disease (GERD), heartburn/acid reflux, gastritis, peptic ulcer disease; reflux symptoms associated with nausea, vomiting or bloating due to delayed gastric emptying.
Rabeprazole is a proton pump inhibitor that reduces stomach acid by blocking the H+/K+ ATPase pump in gastric parietal cells. Domperidone is a peripheral dopamine (D2) receptor antagonist that improves gastric motility and helps relieve nausea/vomiting, thereby reducing reflux symptoms.
Take as prescribed by a doctor. Commonly taken once daily, 15–30 minutes before food (usually before breakfast). Swallow the tablet/capsule whole; do not crush or chew (especially SR/PR domperidone component).
Headache, dizziness, dry mouth, abdominal pain, diarrhoea, constipation, nausea, flatulence, weakness
Not for immediate relief of acute heartburn. Domperidone may increase risk of QT prolongation/serious heart rhythm problems—use with caution in elderly, heart disease, electrolyte imbalance, and avoid if known prolonged QT/arrhythmias. Avoid in moderate–severe liver impairment; caution in kidney disease. Long-term PPI use may cause low magnesium/vitamin B12, increased fracture risk, and may increase risk of C. difficile diarrhoea; seek care for persistent diarrhoea, severe abdominal pain, black stools, or vomiting blood. Use the lowest effective dose for the shortest duration.
Domperidone: strong CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin, erythromycin, ritonavir) and other QT-prolonging drugs (amiodarone, sotalol, quinolones, antipsychotics) increase arrhythmia risk. Rabeprazole: may reduce absorption of drugs needing acidic pH (ketoconazole, itraconazole, posaconazole, iron salts); may affect levels/effects of warfarin, methotrexate (high dose), digoxin; caution with clopidogrel (possible reduced activation).
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep in original blister pack and out of reach of children.
Rablet D SR, Rabekind DSR, Razo DSR, Rabium DSR, Pan-D
At a glance
Good to know
Gastroesophageal reflux disease (GERD), heartburn/acid reflux, gastritis, peptic ulcer disease; reflux symptoms associated with nausea, vomiting or bloating due to delayed gastric emptying.
Headache, dizziness, dry mouth, abdominal pain, diarrhoea, constipation, nausea, flatulence, weakness
Rabeprazole is a proton pump inhibitor that reduces stomach acid by blocking the H+/K+ ATPase pump in gastric parietal cells. Domperidone is a peripheral dopamine (D2) receptor antagonist that improves gastric motility and helps relieve nausea/vomiting, thereby reducing reflux symptoms.
Take as prescribed by a doctor. Commonly taken once daily, 15–30 minutes before food (usually before breakfast). Swallow the tablet/capsule whole; do not crush or chew (especially SR/PR domperidone component).
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep in original blister pack and out of reach of children.
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
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Brand
MANKIND (PHARMA)
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Manufacturer: MANKIND (PHARMA)
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: Manufacturer labeling/pack insert, established medical literature (PPI and domperidone monographs), CDSCO/Indian regulatory guidance on domperidone QT risk
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