Reffozole 40 Tab

Tablet

Gastroesophageal reflux disease (GERD) and heartburn, erosive esophagitis, peptic/duodenal ulcers, Zollinger–Ellison syndrome and other acid hypersecretory conditions; prevention/treatment of NSAID-associated gastric ulcer (as advised by doctor).

Pantoprazole is a proton pump inhibitor (PPI). It irreversibly blocks the H+/K+ ATPase (proton pump) in gastric parietal cells, thereby reducing gastric acid secretion and allowing ulcers/erosions to heal.

Tablet; swallow whole with water (do not crush/chew). Usually taken once daily, preferably 30–60 minutes before food (often before breakfast) or as directed by the doctor; duration depends on condition.

Headache, diarrhoea, nausea, abdominal pain, flatulence, vomiting, dizziness

Use with caution in liver disease. Long-term use may increase risk of low magnesium, vitamin B12 deficiency, bone fractures, and kidney inflammation; seek medical help for persistent diarrhoea (possible C. difficile), severe abdominal pain, black stools, or vomiting blood. May mask symptoms of gastric cancer—consult doctor if alarm symptoms/weight loss occur. Do not stop/start or prolong therapy without medical advice.

Warfarin (INR changes), methotrexate (high-dose; increased levels), digoxin/diuretics (risk of low magnesium), clopidogrel (possible reduced activation; less than omeprazole but caution), atazanavir/nelfinavir (reduced absorption; avoid), ketoconazole/itraconazole/iron salts (reduced absorption), erlotinib (reduced absorption)

Store below 25°C, protected from light and moisture. Keep in original blister pack and out of reach of children.

Pantop 40 Tablet, Pan 40 Tablet, Pantocid 40 Tablet, Pento 40 Tablet, Protonix 40 Tablet