Satrogyl O Dry Syrup

Satrogyl O Dry Syrup contains Satranidazole (75mg/5ml) + Ofloxacin (50mg/5ml). Prescription required.

Treatment of acute infectious diarrhoea and dysentery due to mixed bacterial and protozoal infections; gastroenteritis/intestinal infections where both anaerobic/protozoal and bacterial cover is required, as prescribed.

Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase/topoisomerase IV, stopping bacterial replication. Satranidazole is a nitroimidazole anti-infective active against anaerobic bacteria and protozoa by generating reactive intermediates that damage DNA, leading to cell death.

Oral dry syrup: reconstitute with boiled and cooled water up to the mark, shake well, and use the measuring cup/spoon. Give the dose exactly as prescribed; usually taken after food to reduce stomach upset. Shake well before each dose; complete the full course even if symptoms improve.

Nausea, vomiting, abdominal pain/cramps, diarrhoea, loss of appetite, headache, dizziness, metallic taste, dry mouth, rash

Prescription-only; do not use for viral diarrhoea. Use with caution in liver disease, kidney impairment, history of seizures/CNS disorders, heart rhythm problems (QT prolongation), myasthenia gravis, and in elderly. Risk of tendinitis/tendon rupture and peripheral neuropathy with ofloxacin—stop and seek medical advice if tendon pain, numbness/tingling, or weakness occurs. May cause dizziness—avoid driving if affected. Maintain hydration; seek urgent care for severe diarrhoea, blood in stools, high fever, or symptoms of allergy.

Antacids or supplements containing magnesium/aluminium/calcium/iron/zinc and sucralfate reduce ofloxacin absorption (separate by 2–4 hours); warfarin/other anticoagulants (increased bleeding risk); corticosteroids (increased tendon rupture risk); antiarrhythmics/other QT-prolonging drugs; NSAIDs (may increase seizure risk); antidiabetic medicines/insulin (may affect blood glucose); alcohol (may worsen side effects).

Store dry powder in a cool, dry place below 25°C, protected from moisture and light. After reconstitution, keep tightly closed; store as directed on label (often in a refrigerator or at room temperature) and use within the recommended period; do not freeze.

Satrogyl O Suspension, Satrogyl O Dry Syrup (other pack), Oflox OZ/Satranidazole combinations in suspension (brand varies), Oflox-OZ Suspension (Ofloxacin + Ornidazole), Norflox-TZ Suspension (Norfloxacin + Tinidazole)