Sitagix-D 100/10 mg Tablet

Sitagix-D 100/10 mg Tablet contains Sitagliptin 100 mg + Dapagliflozin 10 mg (tablet). Prescription required.

Type 2 diabetes mellitus: to improve glycaemic control along with diet and exercise in adults when dual therapy is appropriate.

Sitagliptin is a DPP-4 inhibitor that increases incretin levels, enhancing glucose-dependent insulin release and reducing glucagon. Dapagliflozin is an SGLT2 inhibitor that lowers blood glucose by increasing urinary glucose excretion via the kidneys.

Take orally as prescribed by the physician, usually once daily, with or without food. Swallow whole with water; take at the same time each day. Maintain adequate hydration; follow diet/exercise advice and monitor blood glucose regularly.

Urinary tract infection, genital fungal infection, increased urination, thirst, headache, nasopharyngitis, nausea, diarrhoea, dizziness, hypoglycaemia (especially with insulin/sulfonylureas)

Prescription-only antidiabetic. Risk of genital mycotic infections and UTIs; seek care for fever, burning urination, or genital symptoms. May cause dehydration/low blood pressure—use caution in elderly, on diuretics, or with low fluid intake. Rare but serious: pancreatitis (severe abdominal pain), diabetic ketoacidosis (nausea/vomiting, abdominal pain, breathlessness even with near-normal sugars), severe allergic reactions. Monitor kidney function before and during therapy; dapagliflozin efficacy reduces with impaired renal function and may not be recommended in significant kidney disease—follow doctor advice. Temporarily withhold before major surgery or during acute serious illness/fasting to reduce ketoacidosis risk.

Insulin and sulfonylureas (increased hypoglycaemia risk), diuretics (increased dehydration/hypotension risk), other SGLT2 inhibitors or DPP-4 inhibitors (duplication), strong inducers like rifampicin/phenytoin/carbamazepine (may reduce sitagliptin effect), digoxin (sitagliptin may increase levels—monitor), alcohol/excess fasting (increases ketoacidosis risk)

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Istamet-D 100/10 Tablet, Dapa-Sita 10/100 Tablet, Sitagliptin 100 mg + Dapagliflozin 10 mg Tablets (generic equivalents), Janumet-D 100/10 equivalent brands, Zita-Dapa 100/10 Tablet