TUFACNE 10MG TAB

Distributor inventory | Tablet

Treatment of severe, recalcitrant nodular acne (acne conglobata) or acne not responding to adequate courses of standard therapy including systemic antibiotics

Isotretinoin is an oral retinoid that markedly reduces sebum production and shrinks sebaceous glands. It also normalizes follicular keratinization and has anti-inflammatory effects, thereby reducing acne lesions.

Take exactly as prescribed by a dermatologist. Usually taken once or twice daily with food (preferably a fatty meal) to improve absorption; swallow whole with water. Follow the full course and required pregnancy prevention program; do not share medicine.

Dry lips, dry skin, dry eyes, nosebleeds, peeling/skin sensitivity, rash, photosensitivity, headache, muscle/joint pain, increased liver enzymes, increased triglycerides

Teratogenic—contraindicated in pregnancy; strict pregnancy prevention is required (effective contraception before, during and after treatment as advised) and regular pregnancy tests. Avoid blood donation during therapy and for at least 1 month after stopping. Monitor liver function tests and lipid profile; use caution in patients with liver disease, hyperlipidemia, diabetes, depression or history of mood disorders. May cause decreased night vision; caution while driving at night. Avoid excessive sun exposure; use sunscreen. Do not use with tetracyclines (risk of intracranial hypertension) or vitamin A supplements (toxicity).

Tetracyclines (doxycycline/minocycline), vitamin A/retinoid supplements, alcohol (raises triglycerides/liver risk), corticosteroids (bone effects), phenytoin (bone effects), St John’s wort (may reduce contraceptive effectiveness)

Store below 25°C in a cool, dry place away from light and moisture. Keep out of reach of children.

Isotretinoin 10 mg capsules (generic), Isotroin 10 Capsule, Sotret 10 Capsule, Tretiva 10 Capsule, Isonext 10 Capsule