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10`S
Before you take it
Consult doctor (generally use with caution; insulin is preferred in pregnancy; metformin may be used in select cases only under medical supervision).
Voglifin M 0.3 Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Avoid (increases risk of lactic acidosis with metformin and may worsen hypoglycaemia).
Voglifin M 0.3 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Voglifin M 0.3 Tablet may be needed. Please consult your doctor.<br>Use of Voglifin M 0.3 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Voglifin M 0.3 Tablet should be used with caution in patients with liver disease. Dose adjustment of Voglifin M 0.3 Tablet may be needed. Please consult your doctor.<br>Voglifin M 0.3 Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Monograph
Metformin (500mg) + Voglibose (0.3mg)
Type 2 diabetes mellitus (adjunct to diet and exercise) to improve glycaemic control, especially post‑meal blood glucose; used when control is inadequate with single therapy.
Voglibose is an alpha‑glucosidase inhibitor that delays carbohydrate digestion and absorption in the intestine, reducing post‑prandial glucose spikes. Metformin decreases hepatic glucose production and improves insulin sensitivity, thereby lowering fasting and overall blood glucose.
Oral tablet. Take exactly as prescribed. Typically taken with meals: voglibose is taken just before/with the first bite of food; metformin is usually taken with food to reduce stomach upset. Swallow whole with water; do not crush/chew unless advised.
Diarrhoea, nausea, vomiting, abdominal pain, loss of appetite, flatulence, bloating, indigestion, headache, taste disturbance
Prescription medicine. Risk of hypoglycaemia increases when used with insulin or sulfonylureas (may need dose adjustment). Metformin may rarely cause lactic acidosis—risk higher with kidney impairment, dehydration, severe infection, alcohol use, liver disease, heart failure, or hypoxia; stop and seek care if fast breathing, severe weakness, abdominal pain, or drowsiness occur. Monitor kidney function before and during therapy; avoid in severe renal impairment. Temporarily stop metformin before/after iodinated contrast imaging or major surgery as advised by a doctor. Use caution in elderly and in vitamin B12 deficiency (long‑term metformin can reduce B12).
Alcohol (increases lactic acidosis risk with metformin), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), cimetidine, diuretics, ACE inhibitors/ARBs, corticosteroids, beta‑agonists, thyroid hormones, insulin and sulfonylureas (increased hypoglycaemia risk), other antidiabetic medicines
Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.
Voglibose 0.3 mg + Metformin tablets (various brands): Vogli-M 0.3, Voglimet 0.3, Volibo M 0.3, Vobose M 0.3, Voglitor M 0.3
At a glance
Good to know
Type 2 diabetes mellitus (adjunct to diet and exercise) to improve glycaemic control, especially post‑meal blood glucose; used when control is inadequate with single therapy.
Diarrhoea, nausea, vomiting, abdominal pain, loss of appetite, flatulence, bloating, indigestion, headache, taste disturbance
Voglibose is an alpha‑glucosidase inhibitor that delays carbohydrate digestion and absorption in the intestine, reducing post‑prandial glucose spikes. Metformin decreases hepatic glucose production and improves insulin sensitivity, thereby lowering fasting and overall blood glucose.
Oral tablet. Take exactly as prescribed. Typically taken with meals: voglibose is taken just before/with the first bite of food; metformin is usually taken with food to reduce stomach upset. Swallow whole with water; do not crush/chew unless advised.
Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.
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Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: Manufacturer labeling, established medical literature, standard pharmacology references, Indian clinical practice guidance for diabetes, CDSCO-approved drug information (class-level)
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