Vopraz 20MG Tab

Tablet

Treatment of acid-peptic disorders such as gastroesophageal reflux disease (GERD) and erosive esophagitis; healing and prevention of gastric/duodenal ulcers; used as part of therapy for H. pylori eradication when prescribed in combination with antibiotics.

Vonoprazan is a potassium-competitive acid blocker (P-CAB) that directly and reversibly inhibits the gastric H+/K+-ATPase (proton pump). It suppresses stomach acid rapidly and for a longer duration compared with conventional PPIs, helping relieve acidity and promote ulcer/erosion healing.

Take tablet by mouth exactly as prescribed, usually once daily at the same time each day. It may be taken with or without food. Swallow whole with water; do not crush or chew. Duration depends on the condition (e.g., GERD/ulcer healing or as part of H. pylori regimen).

Headache,diarrhoea,abdominal pain,flatulence,nausea,constipation,dizziness

Use with caution in severe liver disease; dose adjustment/medical advice may be needed. Long-term acid suppression may increase risk of low magnesium, vitamin B12 deficiency, and gastrointestinal infections (e.g., C. difficile); seek care for persistent diarrhoea. Consult doctor if alarm symptoms occur (vomiting blood, black stools, unexplained weight loss, difficulty swallowing). Do not self-medicate for prolonged periods.

May reduce absorption of medicines that require an acidic stomach (e.g., ketoconazole, itraconazole, posaconazole, erlotinib, iron salts). May increase exposure of digoxin; monitor if used together. Caution with CYP3A4 inhibitors/inducers (e.g., clarithromycin, rifampicin) which may alter vonoprazan levels. Inform doctor about all medicines including antiplatelets/anticoagulants.

Store below 25°C in a cool, dry place, protected from moisture and direct light. Keep in original blister pack and out of reach of children.

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