Zaper-Dsr Cap

Capsule

Gastroesophageal reflux disease (GERD), heartburn/acid reflux, gastritis, peptic ulcer disease (adjunct), nausea and vomiting associated with acid reflux

Pantoprazole is a proton pump inhibitor that reduces stomach acid secretion by blocking the gastric H+/K+ ATPase pump. Domperidone is a prokinetic/antiemetic that enhances gastric motility and reduces nausea by blocking peripheral dopamine (D2) receptors.

Take orally as directed by a doctor, usually 1 capsule once daily 30 minutes before food (preferably before breakfast). Swallow whole; do not crush or chew as it is enteric-coated/SR.

Headache, dizziness, dry mouth, diarrhea, constipation, abdominal pain, nausea, flatulence, increased prolactin (breast tenderness/galactorrhea), palpitations

Use with caution in liver disease. Domperidone may increase risk of QT prolongation/serious arrhythmias—avoid in patients with known QT prolongation, significant heart disease, electrolyte imbalance, or when using QT-prolonging medicines. Long-term PPI use may be associated with low magnesium/vitamin B12, fracture risk, and C. difficile-associated diarrhea; use lowest effective dose. Seek medical help for black stools, vomiting blood, unexplained weight loss, or persistent symptoms.

QT-prolonging drugs (e.g., amiodarone, sotalol, quinidine, some antipsychotics/antidepressants), strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, erythromycin, ritonavir) increase domperidone levels; warfarin (monitor), methotrexate (high-dose; PPI may increase levels), drugs needing acidic pH for absorption (e.g., ketoconazole, atazanavir, erlotinib), digoxin (monitor), antacids may be spaced if needed

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Pantocid DSR Capsule, Pan DSR Capsule, Sompraz D 40 Capsule, Pent DSR Capsule, Pantodac DSR Capsule