
Actibile 150MG Tab
Zydus Healthcare Pharma - Tablet - 150 mg - 10 S
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Clindamycin (1%w/w) + Adapalene (0.1%w/w)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
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Adalene Nanogel is used for adalene Nanogel Gel is used in the treatment of acne.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Adalene Nanogel contains Clindamycin (1%w/w) + Adapalene (0.1%w/w). It belongs to the Antibacterial agent and Retinoid / keratolytic class of medicines.
Adalene Nanogel Gel is used in the treatment of acne.
Adalene Nanogel Gel is a combination of two medicines: Adapalene and Clindamycin, which treats pimples (acne). Adapalene is a form of vitamin A which prevents accumulation of the sebum (skin’s natural oil), unblocks the pores and allows natural exfoliation of the outer layers of skin. Clindamycin is an antibiotic which works by penetrating into the skin and killing acne-causing bacteria.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Adalene Nanogel are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Adalene Nanogel Gel may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Adalene Nanogel Gel is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | No interaction found/established |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | No interaction found/established |
| Liver | No interaction found/established |
| Habit forming | No |
Finish the whole course even after you feel better. Do not drink any alcohol while taking metronidazole, ornidazole or tinidazole, or for the period after the course that your doctor states — the combination causes severe flushing, vomiting and a racing heart. Report severe or watery loose motions during or after the course rather than treating them yourself. Tetracyclines stain developing teeth and are avoided in young children and in pregnancy. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.
Antacids, iron, zinc and calcium reduce the absorption of tetracyclines — separate them by a couple of hours. Tell your doctor if you take a blood thinner. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness. Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars.
Medicines with the same active ingredient (Clindamycin (1%w/w) + Adapalene (0.1%w/w)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Adalene Nanogel |
|---|---|---|---|
| A Clin GelYAHER PHARMA | gel · 15GM | ₹98 | 74% cheaper |
| Femcinol Adp GelDabur India Ltd | gel · 15GM | ₹268 | 28% cheaper |

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The information on Adalene Nanogel is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.