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Prescription requiredIpca Laboratories Ltd`Anti-acne agent

Adiff Gel

Adapalene

₹194MRP ₹205In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

This medicine needs a prescription.

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Adiff Gel is used for this medicine is used in the treatment of acne, blackheads and whiteheads, pigmentation and rough skin.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Adapalene
Available variants: gel 15GM
Best price: ₹194 (₹12.96 per g)
MRP: ₹205
Prescription: Required
Manufacturer: IPCA LABORATORIES LTD`

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Adiff Gel

Adiff Gel contains Adapalene. It belongs to the Retinoid / keratolytic class of medicines.

Uses of Adiff Gel

  • This medicine is used in the treatment of acne
  • blackheads and whiteheads
  • pigmentation and rough skin.

Key benefits

  • Clears and prevents acne
  • Improves skin texture and marks over time

How Adiff Gel works

Adapalene unblocks the pores and speeds up the turnover of skin cells, so fewer spots form.

How to take Adiff Gel

Clean and dry the affected area, then apply a thin layer and rub it in gently. Wash your hands before and after use, unless your hands are the area being treated. This is for use on the skin only — do not swallow it. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Adiff Gel

Most side effects of Adiff are mild and settle as the body adjusts. Reported side effects include:

  • Dryness
  • Peeling
  • Redness
  • Burning or stinging
  • Increased sensitivity to sunlight

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Adiff Gel

PregnancyNot recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant.
BreastfeedingNot recommended while breastfeeding.
AlcoholAlcohol may worsen the side effects of this medicine. Limit it.
DrivingNot expected to affect your ability to drive.
KidneyUse with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds.

Do not take Adiff if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.

Interactions with other medicines

Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.

How to store Adiff Gel

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Expert advice for Adiff Gel

Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars.

Manufacturer and class

Manufacturer:
IPCA LABORATORIES LTD`
Therapeutic class:
Anti-acne agent
Drug class:
Retinoid / keratolytic

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Adiff Gel FAQs

What is Adiff Gel used for?
Adiff Gel is commonly used for This medicine is used in the treatment of acne, blackheads and whiteheads, pigmentation and rough skin. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Adiff Gel?
Adiff Gel contains Adapalene. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Adiff Gel?
Clean and dry the affected area, then apply a thin layer and rub it in gently. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Adiff Gel work?
Adapalene unblocks the pores and speeds up the turnover of skin cells, so fewer spots form.
Is Adiff Gel a prescription medicine?
Yes. Adiff Gel is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Adiff Gel?
The side effects reported most often with Adiff are Dryness, Peeling, Redness, Burning or stinging, Increased sensitivity to sunlight. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Adiff Gel be taken during pregnancy?
Not recommended in pregnancy — it may harm the developing baby. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Adiff.
Can I drink alcohol while taking Adiff Gel?
Alcohol may worsen the side effects of this medicine.
What if I miss a dose of Adiff Gel?
Apply it as soon as you remember.
Is Adiff Gel habit forming?
No. Adiff Gel is not known to be habit forming when taken as prescribed.
How much does Adiff Gel cost on PingMeDoc Pharmacy?
Adiff Gel starts at ₹194 (MRP ₹205) on PingMeDoc Pharmacy. Available in gel 15GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Adiff Gel?
Adiff Gel is manufactured by IPCA LABORATORIES LTD`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Adiff Gel delivered?
Adiff Gel is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Adiff Gel, Quick facts

Salt
Adapalene
Form
gel
Best price
₹194 (₹12.96 per g)
MRP
₹205
Prescription
Required (Rx)
Brand
IPCA LABORATORIES LTD`
Manufacturer
IPCA LABORATORIES LTD`
Therapeutic class
Anti-acne agent
Drug class
Retinoid / keratolytic
Habit forming
No
Variants
gel 15GM
Delivery
Standard across India

References

The information on Adiff Gel is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Adiff Gel.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.