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Prescription requiredFourrts India Laboratories Pvt LtdEmollient and Analgesic and anti-inflammatory

Autolyse Ointment

Urea (100mg) + Papain (521700IU)

₹226MRP ₹231In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Autolyse Ointment is used for this medicine is used in the treatment of dry skin, eczema, skin barrier repair, itching due to dryness, pain and swelling, inflammatory arthritis, gout and recovery after injury or surgery.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Urea (100mg) + Papain (521700IU)
Available variants: ointment 100mg + 521700IU 15GM
Best price: ₹226 (₹15.09 per g)
MRP: ₹231
Prescription: Required
Manufacturer: FOURTS (INDIA) LAB (P) LTD

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Autolyse Ointment.

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Autolyse Ointment

ointment - 100mg + 521700IU - 15 g

₹226

₹15.09 per g

  • Cariheal Oint 15GM

    ANTHEM BIOPHARMA · ointment - 15 gm - 15 g · Rx

    ₹162

    ₹10.80 per g

    Save 28%
Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Autolyse Ointment. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Autolyse Ointment

Autolyse Ointment contains Urea (100mg) + Papain (521700IU). It belongs to the Moisturiser / skin barrier repair and Enzyme / disease-modifying anti-rheumatic agent class of medicines.

Uses of Autolyse Ointment

  • This medicine is used in the treatment of dry skin
  • eczema
  • skin barrier repair
  • itching due to dryness
  • pain and swelling
  • inflammatory arthritis
  • gout and recovery after injury or surgery.

Key benefits

  • The foundation of eczema and dry-skin care
  • Reduces how often a steroid cream is needed
  • Safe for long-term daily use
  • Reduces swelling and joint damage over time
  • Improves function in inflammatory disease

How Autolyse Ointment works

This medicine combines 2 active ingredients: Urea and Papain. Urea holds water in the skin and restores the barrier that dry, damaged skin has lost. Papain reduces inflammation and the swelling that comes with injury, surgery or an inflammatory joint disease.

How to take Autolyse Ointment

Clean and dry the affected area, then apply a thin layer and rub it in gently. Wash your hands before and after use, unless your hands are the area being treated. This is for use on the skin only — do not swallow it. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine is not a realistic risk from a moisturiser used on the skin. It can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Autolyse Ointment

Most side effects of Autolyse are mild and settle as the body adjusts. Reported side effects include:

  • Mild stinging on broken skin
  • Greasy feel
  • Rarely
  • a rash
  • Nausea
  • Stomach upset
  • Loose motions
  • Rash
  • Raised liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Autolyse Ointment

PregnancyNot recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant.
BreastfeedingNot recommended while breastfeeding.
AlcoholDo not drink alcohol while taking this medicine.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyConsult your doctor if you have kidney disease.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Apply generously and often — several times a day, and always within a few minutes of a bath while the skin is still damp. Some paraffin-based emollients are flammable when they soak into clothing and bedding. Keep away from open flames and cigarettes. Stop if the skin becomes more red, itchy or sore after use. Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.

Do not take Autolyse if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

No significant interactions are expected. Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.

How to store Autolyse Ointment

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Expert advice for Autolyse Ointment

Use lukewarm water, a soap substitute and short baths. Smooth it on in the direction the hair grows rather than rubbing it in hard. Keep using it when the skin looks normal — that is what prevents the next flare. Keep every monitoring blood test appointment. Carry a note of the medicine and its schedule, especially for weekly dosing.

Manufacturer and class

Manufacturer:
FOURTS (INDIA) LAB (P) LTD
Therapeutic class:
Emollient and Analgesic and anti-inflammatory
Drug class:
Moisturiser / skin barrier repair and Enzyme / disease-modifying anti-rheumatic agent

Substitutes for Autolyse Ointment

Medicines with the same active ingredient (Urea (100mg) + Papain (521700IU)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Autolyse Ointment
Cariheal Ointment 15 gANTHEM BIOPHARMAointment · 15GM₹16228% cheaper
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Autolyse Ointment FAQs

What is Autolyse Ointment used for?
Autolyse Ointment is commonly used for This medicine is used in the treatment of dry skin, eczema, skin barrier repair, itching due to dryness, pain and swelling, inflammatory arthritis, gout and recovery after injury or surgery. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Autolyse Ointment?
Autolyse Ointment contains Urea (100mg) + Papain (521700IU). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Autolyse Ointment?
Clean and dry the affected area, then apply a thin layer and rub it in gently. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Autolyse Ointment work?
This medicine combines 2 active ingredients: Urea and Papain.
Is Autolyse Ointment a prescription medicine?
Yes. Autolyse Ointment is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Autolyse Ointment?
The side effects reported most often with Autolyse are Mild stinging on broken skin, Greasy feel, Rarely, a rash, Nausea. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Autolyse Ointment be taken during pregnancy?
Not recommended in pregnancy — it may harm the developing baby. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Autolyse.
Can I drink alcohol while taking Autolyse Ointment?
Do not drink alcohol while taking this medicine.
What if I miss a dose of Autolyse Ointment?
Apply it as soon as you remember.
Is Autolyse Ointment habit forming?
No. Autolyse Ointment is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Autolyse Ointment?
Cariheal Ointment 15 g has the same active ingredient and strength and is listed from ₹162 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Autolyse Ointment cost on PingMeDoc Pharmacy?
Autolyse Ointment starts at ₹226 (MRP ₹231) on PingMeDoc Pharmacy. Available in ointment 100mg + 521700IU 15GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Autolyse Ointment?
Autolyse Ointment is manufactured by FOURTS (INDIA) LAB (P) LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Autolyse Ointment delivered?
Autolyse Ointment is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Autolyse Ointment, Quick facts

Salt
Urea (100mg) + Papain (521700IU)
Form
ointment
Best price
₹226 (₹15.09 per g)
MRP
₹231
Prescription
Required (Rx)
Brand
Fourrts India Laboratories Pvt Ltd
Manufacturer
FOURTS (INDIA) LAB (P) LTD
Therapeutic class
Emollient and Analgesic and anti-inflammatory
Drug class
Moisturiser / skin barrier repair and Enzyme / disease-modifying anti-rheumatic agent
Habit forming
No
Variants
ointment 100mg + 521700IU 15GM
Delivery
Standard across India

References

The information on Autolyse Ointment is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Autolyse Ointment.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.