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Fourrts India Laboratories Pvt Ltd - Tablet - 10 S
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Urea (100mg) + Papain (521700IU)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Autolyse Ointment is used for this medicine is used in the treatment of dry skin, eczema, skin barrier repair, itching due to dryness, pain and swelling, inflammatory arthritis, gout and recovery after injury or surgery.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Autolyse Ointment.
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Autolyse Ointment
ointment - 100mg + 521700IU - 15 g
₹226
₹15.09 per g
ANTHEM BIOPHARMA · ointment - 15 gm - 15 g · Rx
₹162
₹10.80 per g
A substitute contains the same active ingredient (salt), in the same strength, as Autolyse Ointment. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Autolyse Ointment contains Urea (100mg) + Papain (521700IU). It belongs to the Moisturiser / skin barrier repair and Enzyme / disease-modifying anti-rheumatic agent class of medicines.
This medicine combines 2 active ingredients: Urea and Papain. Urea holds water in the skin and restores the barrier that dry, damaged skin has lost. Papain reduces inflammation and the swelling that comes with injury, surgery or an inflammatory joint disease.
Clean and dry the affected area, then apply a thin layer and rub it in gently. Wash your hands before and after use, unless your hands are the area being treated. This is for use on the skin only — do not swallow it. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine is not a realistic risk from a moisturiser used on the skin. It can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Autolyse are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant. |
|---|---|
| Breastfeeding | Not recommended while breastfeeding. |
| Alcohol | Do not drink alcohol while taking this medicine. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Apply generously and often — several times a day, and always within a few minutes of a bath while the skin is still damp. Some paraffin-based emollients are flammable when they soak into clothing and bedding. Keep away from open flames and cigarettes. Stop if the skin becomes more red, itchy or sore after use. Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.
No significant interactions are expected. Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.
Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.
Use lukewarm water, a soap substitute and short baths. Smooth it on in the direction the hair grows rather than rubbing it in hard. Keep using it when the skin looks normal — that is what prevents the next flare. Keep every monitoring blood test appointment. Carry a note of the medicine and its schedule, especially for weekly dosing.
Medicines with the same active ingredient (Urea (100mg) + Papain (521700IU)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Autolyse Ointment |
|---|---|---|---|
| Cariheal Ointment 15 gANTHEM BIOPHARMA | ointment · 15GM | ₹162 | 28% cheaper |
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The information on Autolyse Ointment is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.