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OTC · No prescriptionPiramal HealthcareAntipruritic / Skin protectant

Caladryl Lotion

Calamine 8% w/v, Zinc oxide 8% w/v, Diphenhydramine hydrochloride 1% w/v (typical Caladryl lotion composition; may vary by pack)

Caladryl Lotion is used for itching and irritation due to insect bites, allergic skin rashes, urticaria, prickly heat, mild sunburn, chickenpox-associated itching, contact dermatitis.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹75₹1.15 per ml
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Calamine 8% w/v, Zinc oxide 8% w/v, Diphenhydramine hydrochloride 1% w/v (typical Caladryl lotion composition; may vary by pack)
Available variants: lotion 65 Ml, lotion 125 Ml
Best price: ₹75 (₹1.15 per ml)
Prescription: Not required
Manufacturer: PIRAMAL HEALTHCARE

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Caladryl Lotion

Caladryl Lotion contains Calamine 8% w/v, Zinc oxide 8% w/v, Diphenhydramine hydrochloride 1% w/v (typical Caladryl lotion composition; may vary by pack). It belongs to the Topical antihistamine + skin protectants class of medicines.

Uses of Caladryl Lotion

  • Itching and irritation due to insect bites
  • allergic skin rashes
  • urticaria
  • prickly heat
  • mild sunburn
  • chickenpox-associated itching
  • contact dermatitis

Key benefits

  • Relieves itching
  • Soothes irritated skin
  • Reduces redness and rash discomfort
  • Provides cooling protective layer

How Caladryl Lotion works

Calamine and zinc oxide have soothing and mild astringent/protective effects that calm irritated skin. Diphenhydramine is an antihistamine that reduces itching by blocking H1 receptors in the skin.

How to take Caladryl Lotion

For external use only. Shake well and apply a thin layer to affected area 2-4 times daily or as directed. Avoid eyes, mouth and broken skin; wash hands after application.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Caladryl as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Caladryl than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Caladryl Lotion

Most side effects of Caladryl are mild and settle as the body adjusts. Reported side effects include:

  • Skin dryness
  • mild burning or stinging
  • irritation
  • rash
  • allergic reaction

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Caladryl Lotion

PregnancyGenerally safe
AlcoholNo known interaction
Habit formingNo

Warnings and precautions

Do not apply on large areas, severely broken skin, or under occlusive dressings unless advised. Stop use and consult a doctor if rash worsens, signs of infection occur, or symptoms persist. Children: use cautiously and avoid ingestion.

Interactions with other medicines

No significant systemic interactions expected with topical use; avoid using multiple topical antihistamines/irritants on the same area

How to store Caladryl Lotion

Store below 25°C, tightly closed, protect from heat and direct sunlight. Do not freeze.

Manufacturer and class

Manufacturer:
PIRAMAL HEALTHCARE
Therapeutic class:
Antipruritic / Skin protectant
Drug class:
Topical antihistamine + skin protectants

Substitutes for Caladryl Lotion

Medicines with the same active ingredient (Calamine 8% w/v, Zinc oxide 8% w/v, Diphenhydramine hydrochloride 1% w/v (typical Caladryl lotion composition; may vary by pack)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Caladryl Lotion
Markal Calamine LotionMark Indialotion · 60ML₹11047% more
See all substitutes and alternatives

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Caladryl Lotion FAQs

What is Caladryl Lotion used for?
Caladryl Lotion is commonly used for Itching and irritation due to insect bites, allergic skin rashes, urticaria, prickly heat, mild sunburn, chickenpox-associated itching, contact dermatitis. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Caladryl Lotion?
Caladryl Lotion contains Calamine 8% w/v, Zinc oxide 8% w/v, Diphenhydramine hydrochloride 1% w/v (typical Caladryl lotion composition; may vary by pack). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Caladryl Lotion?
For external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Caladryl Lotion work?
Calamine and zinc oxide have soothing and mild astringent/protective effects that calm irritated skin.
Is Caladryl Lotion a prescription medicine?
No. Caladryl Lotion is available over the counter (OTC), no prescription is required. However, it is always safer to consult a doctor or pharmacist before use.
What are the common side effects of Caladryl Lotion?
The side effects reported most often with Caladryl are Skin dryness, mild burning or stinging, irritation, rash, allergic reaction. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Caladryl Lotion be taken during pregnancy?
Generally safe Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Caladryl.
Can I drink alcohol while taking Caladryl Lotion?
No known interaction
What if I miss a dose of Caladryl Lotion?
Take the missed dose of Caladryl as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.
Is Caladryl Lotion habit forming?
No. Caladryl Lotion is not known to be habit forming when taken as prescribed.
How much does Caladryl Lotion cost on PingMeDoc Pharmacy?
Caladryl Lotion starts at ₹75 on PingMeDoc Pharmacy. Available in lotion 65 Ml, lotion 125 Ml. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Caladryl Lotion?
Caladryl Lotion is manufactured by PIRAMAL HEALTHCARE. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Caladryl Lotion delivered?
Caladryl Lotion is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Caladryl Lotion, Quick facts

Salt
Calamine 8% w/v, Zinc oxide 8% w/v, Diphenhydramine hydrochloride 1% w/v (typical Caladryl lotion composition; may vary by pack)
Form
lotion
Best price
₹75 (₹1.15 per ml)
Prescription
Not required (OTC)
Brand
PIRAMAL HEALTHCARE
Manufacturer
PIRAMAL HEALTHCARE
Therapeutic class
Antipruritic / Skin protectant
Drug class
Topical antihistamine + skin protectants
Habit forming
No
Variants
lotion 65 Ml, lotion 125 Ml
Delivery
Standard across India

References

The information on Caladryl Lotion is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling
  2. Indian Pharmacopoeia (excipients/actives where applicable), established medical literature
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Caladryl Lotion.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.