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Intas Pharmaceuticals Ltd - Tablet - 250mg - 10 S
Save ₹1415
Prescription required
Clomipramine (25mg)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Clonil 25 mg Tablet is used for treatment of Depression Treatment of Obsessive-compulsive disorder Treatment of Phobia.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Clonil 25 mg Tablet contains Clomipramine (25mg). It belongs to the Antidepressant class of medicines.
Treatment of Depression Treatment of Obsessive-compulsive disorder Treatment of Phobia
Clonil 25 mg Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. CLOnil 25 Tablet should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of CLOnil 25 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Clonil are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Clonil 25 mg Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Clonil 25 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Clonil 25 mg Tablet may cause excessive drowsiness and calmness with alcohol. |
| Driving | Driving UNSAFE |
| Kidney | There is limited information available on the use of Clonil 25 mg Tablet in patients with kidney disease. Please consult your doctor.<br>Caution should be exercised in patients with underlying kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine. |
| Liver | Clonil 25 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Clonil 25 mg Tablet may be needed. Please consult your doctor.<br>Regular monitoring of liver function tests is advisable when you are taking this medicine. |
| Habit forming | No |
These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take CLOnil 25 Tablet at the same time every day to build a routine and avoid missed doses. Do not stop the medicine suddenly, even if you feel better; always consult your doctor before making changes. Avoid driving or operating heavy machines until you know how it affects you, as CLOnil 25 Tablet may cause drowsiness. Limit or avoid alcohol, as it can increase drowsiness and side effects. Make sure to attend all follow-up visits with the doctor to monitor your dose and progress.
Medicines with the same active ingredient (Clomipramine (25mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Clonil 25 mg Tablet |
|---|---|---|---|
| Clofranil 25 mg TabletSUN PHARMA | tablet · 10`s | ₹64 | 33% cheaper |

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The information on Clonil 25 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.