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Prescription requiredIntas Pharmaceuticals LtdAntidepressant

Clonil 50 Tablet

Clomipramine (50mg)

₹292MRP ₹307In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Clonil 50 Tablet is used for clonil 50 Tablet is used in the treatment of depression and obsessive-compulsive disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Clomipramine (50mg)
Available variants: tablet 50mg 15`S
Best price: ₹292 (₹19.46 per tablet)
MRP: ₹307
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Clonil 50 Tablet

Clonil 50 Tablet contains Clomipramine (50mg). It belongs to the Antidepressant class of medicines.

Uses of Clonil 50 Tablet

Clonil 50 Tablet is used in the treatment of depression and obsessive-compulsive disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

Key benefits

  • Effective for depression and anxiety disorders
  • Also relieves nerve pain and prevents migraine
  • Usually taken once a day

How Clonil 50 Tablet works

Clonil 50 Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

How to take Clonil 50 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clonil 50 Tablet is to be taken with food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Clonil 50 Tablet

Most side effects of Clonil are mild and settle as the body adjusts. Reported side effects include:

  • Sleepiness Blurred vision Dryness in mouth Difficulty in urination Constipation Orthostatic hypotension (sudden lowering of blood pressure on standing) Weight gain Increased heart rate

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Clonil 50 Tablet

PregnancyClonil 50 Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingClonil 50 Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
AlcoholClonil 50 Tablet may cause excessive drowsiness and calmness with alcohol.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyThere is limited information available on the use of Clonil 50 Tablet in patients with kidney disease. Please consult your doctor.<br>Caution should be exercised in patients with underlying kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
LiverClonil 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Clonil 50 Tablet may be needed. Please consult your doctor.<br>Regular monitoring of liver function tests is advisable when you are taking this medicine.
Habit formingNo

Warnings and precautions

These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.

Do not take Clonil if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.

How to store Clonil 50 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Clonil 50 Tablet

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>The main dose should be taken at night as this drug may produce drowsiness or sleepiness.</div></li> <li>It can take 4 to 6 weeks for D.D.Pramine 50 mg Tablet to start working.</li> <li>You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.</li> <li>If your doctor asks you to stop D.D.Pramine 50 mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.</li> <li>Avoid driving or operating machinery as it may decrease alertness.</li> <li>Avoid consuming alcohol when taking the D.D.Pramine 50 mg Tablet, as it may cause excessive drowsiness and calmness.</li> <li>The addiction/dependence potential of D.D.Pramine 50 mg Tablet is very less.</li> <li>It may be extremely dangerous in overdose.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
INTAS PHARMACEUTICALS`
Therapeutic class:
Antidepressant
Drug class:
Antidepressant

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Clonil 50 Tablet FAQs

What is Clonil 50 Tablet used for?
Clonil 50 Tablet is commonly used for Clonil 50 Tablet is used in the treatment of depression and obsessive-compulsive disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Clonil 50 Tablet?
Clonil 50 Tablet contains Clomipramine (50mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Clonil 50 Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Clonil 50 Tablet work?
Clonil 50 Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Is Clonil 50 Tablet a prescription medicine?
Yes. Clonil 50 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Clonil 50 Tablet?
The side effects reported most often with Clonil are Sleepiness Blurred vision Dryness in mouth Difficulty in urination Constipation Orthostatic hypotension (sudden lowering of blood pressure on standing) Weight gain Increased heart rate. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Clonil 50 Tablet be taken during pregnancy?
Clonil 50 Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Clonil.
Can I drink alcohol while taking Clonil 50 Tablet?
Clonil 50 Tablet may cause excessive drowsiness and calmness with alcohol.
What if I miss a dose of Clonil 50 Tablet?
Take it as soon as you remember.
Is Clonil 50 Tablet habit forming?
No. Clonil 50 Tablet is not known to be habit forming when taken as prescribed.
How much does Clonil 50 Tablet cost on PingMeDoc Pharmacy?
Clonil 50 Tablet starts at ₹292 (MRP ₹307) on PingMeDoc Pharmacy. Available in tablet 50mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Clonil 50 Tablet?
Clonil 50 Tablet is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Clonil 50 Tablet delivered?
Clonil 50 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Clonil 50 Tablet, Quick facts

Salt
Clomipramine (50mg)
Form
tablet
Best price
₹292 (₹19.46 per tablet)
MRP
₹307
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Intas Pharmaceuticals Ltd
Manufacturer
INTAS PHARMACEUTICALS`
Therapeutic class
Antidepressant
Drug class
Antidepressant
Habit forming
No
Variants
tablet 50mg 15`S
Delivery
Standard across India

References

The information on Clonil 50 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Clonil 50 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.