
Abione Tab
Intas Pharmaceuticals Ltd - Tablet - 250mg - 10 S
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Prescription required
Clomipramine (50mg)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Clonil 50 Tablet is used for clonil 50 Tablet is used in the treatment of depression and obsessive-compulsive disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Clonil 50 Tablet contains Clomipramine (50mg). It belongs to the Antidepressant class of medicines.
Clonil 50 Tablet is used in the treatment of depression and obsessive-compulsive disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.
Clonil 50 Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clonil 50 Tablet is to be taken with food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Clonil are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Clonil 50 Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Clonil 50 Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby. |
| Alcohol | Clonil 50 Tablet may cause excessive drowsiness and calmness with alcohol. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | There is limited information available on the use of Clonil 50 Tablet in patients with kidney disease. Please consult your doctor.<br>Caution should be exercised in patients with underlying kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine. |
| Liver | Clonil 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Clonil 50 Tablet may be needed. Please consult your doctor.<br>Regular monitoring of liver function tests is advisable when you are taking this medicine. |
| Habit forming | No |
These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>The main dose should be taken at night as this drug may produce drowsiness or sleepiness.</div></li> <li>It can take 4 to 6 weeks for D.D.Pramine 50 mg Tablet to start working.</li> <li>You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.</li> <li>If your doctor asks you to stop D.D.Pramine 50 mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.</li> <li>Avoid driving or operating machinery as it may decrease alertness.</li> <li>Avoid consuming alcohol when taking the D.D.Pramine 50 mg Tablet, as it may cause excessive drowsiness and calmness.</li> <li>The addiction/dependence potential of D.D.Pramine 50 mg Tablet is very less.</li> <li>It may be extremely dangerous in overdose.</li></ul></div></div></div></div></div></div>

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The information on Clonil 50 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.