Ace Revelol 25/2.5
IPCA Laboratories Ltd - 10 S
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Prescription requiredIpca Laboratories Ltd`Antiepileptic / Mood stabilizer / Antimigraine prophylactic
Divalrate ER 500
Divalproex (500mg)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Divalrate ER 500 is used for treatment of epilepsy/seizure disorders (partial and generalized seizures), management of manic episodes associated with bipolar disorder, prevention of migraine headaches (prophylaxis).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: Divalproex (500mg)
Available variants: NA 10`S
Best price: ₹70
MRP: ₹74
Prescription: Required
Manufacturer: IPCA LABORATORIES LTD`
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Divalrate ER 500
Divalrate ER 500 contains Divalproex (500mg). It belongs to the Anticonvulsant (valproate) class of medicines.
Uses of Divalrate ER 500
- Treatment of epilepsy/seizure disorders (partial and generalized seizures)
- management of manic episodes associated with bipolar disorder
- prevention of migraine headaches (prophylaxis)
Key benefits
- Controls and prevents seizures
- Helps treat acute mania in bipolar disorder
- Prevents migraine attacks
- Stabilizes abnormal brain electrical activity
How Divalrate ER 500 works
Divalproex sodium dissociates to valproate in the body. Valproate increases brain GABA levels and modulates sodium and calcium channels, stabilizing neuronal firing and reducing abnormal electrical activity.
How to take Divalrate ER 500
Oral extended-release tablet; swallow whole with water (do not crush/chew/split). Take once daily at the same time each day, with or without food (with food if stomach upset). Dose and duration as prescribed; do not stop abruptly.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
If you miss a dose of Divalrate 500mg Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
If you take too much
An overdose of this medicine can cause deep unconsciousness, slowed breathing and dangerous heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Divalrate ER 500
Most side effects of Divalrate ER are mild and settle as the body adjusts. Reported side effects include:
- Nausea
- vomiting
- abdominal pain
- diarrhea
- indigestion
- increased appetite
- weight gain
- tremor
- dizziness
- drowsiness
- headache
- hair loss
- blurred vision
- low platelet count
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Divalrate ER 500
| Pregnancy | Not recommended (high risk of birth defects and neurodevelopmental disorders); use only if no suitable alternative and under specialist care |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Avoid |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver UNSAFE |
| Habit forming | No |
Warnings and precautions
Contraindicated in active liver disease or significant hepatic dysfunction; risk of severe hepatotoxicity (especially in first 6 months), pancreatitis, hyperammonemic encephalopathy, thrombocytopenia and bleeding. Monitor liver function tests, CBC/platelets, and ammonia if symptoms occur. Can cause sedation—use caution while driving. Do not stop suddenly due to seizure risk. Use caution in elderly, renal impairment, and in patients with metabolic/urea-cycle disorders.
Do not take Divalrate ER if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Valproate-containing medicines are contraindicated in pregnancy for epilepsy unless no alternative exists, and in all women of childbearing potential without a pregnancy prevention programme. Several are not suitable in significant liver disease.
Interactions with other medicines
Carbamazepine, phenytoin, phenobarbital, lamotrigine (increased rash risk), topiramate (hyperammonemia), aspirin (increases valproate levels/bleeding), warfarin/anticoagulants (bleeding), benzodiazepines and other CNS depressants (added sedation), alcohol (added CNS depression), rifampicin (reduced levels)
How to store Divalrate ER 500
Store below 25°C in a dry place, protected from light and moisture. Keep in original pack and out of reach of children.
Expert advice for Divalrate ER 500
Take your medication regularly as directed by your doctor, as missing doses can trigger seizures. Take it at the same time every day to maintain consistent levels in your body. It can be taken with or without food; however, consider taking it with food to avoid an upset stomach. Do not change the brand of your medicine, and make sure that you have a sufficient amount of medicine present with you. It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you. Monitor your weight during treatment with this medicine, as it can cause weight gain. Your doctor may get regular blood tests done to monitor how the medication is affecting your body. Inform your doctor if you notice yellowing of the eyes or skin, dark urine, or stomach pain. Avoid consuming alcohol when taking Divalrate 500mg Tablet ER, as it may cause excessive sleepiness or drowsiness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior. Do not take Divalrate 500mg Tablet ER if you are pregnant or planning to conceive or breastfeed.
Manufacturer and class
- Manufacturer:
- IPCA LABORATORIES LTD`
- Therapeutic class:
- Antiepileptic / Mood stabilizer / Antimigraine prophylactic
- Drug class:
- Anticonvulsant (valproate)
- Chemical class:
- Methyl- branched fatty acids
Substitutes for Divalrate ER 500
Medicines with the same active ingredient (Divalproex (500mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Divalrate ER 500 |
|---|---|---|---|
| Diprowize OD 500 TabletICON PHARMA | tablet · 10`S | ₹147 | 110% more |
| Divalgress ER 500 mg TabletLARENON | tablet · 10`S | ₹164 | 134% more |
| Divalex OD 500 mg TabletCRESCENT FORUMULATIONS PVT LTD | tablet · 10`S | ₹175 | 150% more |
| Divalpro 500 TabletZYDUS HEALTHCARE PHARMA | tablet · 10`S | ₹205 | 192% more |
| Desval ER 1 g TabletERIS LIFE SCIENCES PVT LTD | tablet · 10`S | ₹212 | 204% more |
| Trend XR 500 mg TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹216 | 209% more |
| Valkem OD 500 TabletALKEM LAB | tablet · 10`S | ₹233 | 233% more |
| Divaa-500Intas Pharmaceuticals Ltd | 15`S | ₹250 | 257% more |
| Dayo OD 500LUPIN LAB | 10`S | ₹251 | 259% more |
| Divaa-OD 500 mg TabletIntas Pharmaceuticals Ltd | tablet · 15`S | ₹293 | 319% more |
| Depakote XR 500 mgCIPLA LIMITED | 15 | ₹423 | 504% more |
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Divalrate ER 500 FAQs
What is Divalrate ER 500 used for?
Divalrate ER 500 is commonly used for Treatment of epilepsy/seizure disorders (partial and generalized seizures), management of manic episodes associated with bipolar disorder, prevention of migraine headaches (prophylaxis). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Divalrate ER 500?
Divalrate ER 500 contains Divalproex (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Divalrate ER 500?
Oral extended-release tablet; swallow whole with water (do not crush/chew/split). Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Divalrate ER 500 work?
Divalproex sodium dissociates to valproate in the body.
Is Divalrate ER 500 a prescription medicine?
Yes. Divalrate ER 500 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Divalrate ER 500?
The side effects reported most often with Divalrate ER are Nausea, vomiting, abdominal pain, diarrhea, indigestion. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Divalrate ER 500 be taken during pregnancy?
Not recommended (high risk of birth defects and neurodevelopmental disorders); use only if no suitable alternative and under specialist care Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Divalrate ER.
Can I drink alcohol while taking Divalrate ER 500?
Avoid
What if I miss a dose of Divalrate ER 500?
If you miss a dose of Divalrate 500mg Tablet ER, take it as soon as possible.
Is Divalrate ER 500 habit forming?
No. Divalrate ER 500 is not known to be habit forming when taken as prescribed.
How much does Divalrate ER 500 cost on PingMeDoc Pharmacy?
Divalrate ER 500 starts at ₹70 (MRP ₹74) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Divalrate ER 500?
Divalrate ER 500 is manufactured by IPCA LABORATORIES LTD`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Divalrate ER 500 delivered?
Divalrate ER 500 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Divalrate ER 500, Quick facts
- Salt
- Divalproex (500mg)
- Best price
- ₹70
- MRP
- ₹74
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- IPCA LABORATORIES LTD`
- Manufacturer
- IPCA LABORATORIES LTD`
- Therapeutic class
- Antiepileptic / Mood stabilizer / Antimigraine prophylactic
- Drug class
- Anticonvulsant (valproate)
- Chemical class
- Methyl- branched fatty acids
- Action class
- Sodium Channel Modulators- Antiepileptic drugs (AEDs)
- Habit forming
- No
- Variants
- NA 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- Manufacturer labeling, established medical literature (valproate/divalproex), standard clinical guidelines
- Indian Pharmacopoeia/monographs where applicable
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Divalrate ER 500.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.