Dolostat MR Tablet

Composition of Dolostat MR Tablet

Dolostat MR Tablet contains Aceclofenac (100mg) + Paracetamol (325mg) + Chlorzoxazone (500mg). It belongs to the Non-steroidal anti-inflammatory drug, Para-aminophenol derivative and Centrally acting muscle relaxant class of medicines.

Uses of Dolostat MR Tablet

Treatment of Muscular pain

Key benefits

• In Treatment of Muscular pain Dolostat MR 100 mg/325 mg/500 mg Tablet is a combination medicine that is used to relieve pain
• inflammation
• and swelling in conditions that affect muscles. Also
• it effectively relieves muscle stiffness or spasm
• thereby improving muscle movement. It works by blocking chemical messengers in the brain that tell us we have pain. Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general
• you should take the lowest dose that works
• for the shortest possible time. This will help you to go about your daily activities more easily and have a better
• more active
• quality of life.

How Dolostat MR Tablet works

Dolostat MR 100 mg/325 mg/500 mg Tablet is a combination of two pain relieving medicines (Aceclofenac and Paracetamol) and a muscle relaxant (Chlorzoxazone). The pain relieving medicines work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm, thereby improving muscle movement.

How to take Dolostat MR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dolostat MR 100 mg/325 mg/500 mg Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Dolostat MR 100 mg/325 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. It can cause deep drowsiness, muscle weakness, a fall in blood pressure and slowed breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Dolostat MR Tablet

Most side effects of Dolostat MR are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Dolostat MR Tablet

Warnings and precautions

Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five. This medicine causes drowsiness. Do not drive or operate machinery until you know how it affects you. Use it for the short course your doctor has prescribed — these are not intended for long-term use. Do not stop a long course abruptly without asking your doctor.

Do not take Dolostat MR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with severe liver disease, except under medical supervision. Not for people with myasthenia gravis or severe liver disease.

Interactions with other medicines

Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it. Alcohol, sleeping tablets, antihistamines and opioid painkillers all add to the drowsiness, sometimes dangerously.

How to store Dolostat MR Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Dolostat MR Tablet

Avoid consuming alcohol when taking Dolostat MR 100 mg/325 mg/500 mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage. Older adults may have increased drowsiness, confusion, and higher risk of falling as a result of taking Dolostat MR 100 mg/325 mg/500 mg Tablet. Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Manufacturer and class

Manufacturer:

BLUE CROSS LABORATORIES LTD`

Therapeutic class:

PAIN ANALGESICS

Drug class:

Non-steroidal anti-inflammatory drug, Para-aminophenol derivative and Centrally acting muscle relaxant