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Prescription requiredLupin LabANTI DIABETIC

Gibtulio Met XR 25/1000 mg Tablet

Empagliflozin (12.5mg) + Metformin (500mg)

Gibtulio Met XR 25/1000 mg Tablet is used for treatment of Type 2 diabetes mellitus.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

₹183₹18.28 per tablet
100% genuine medicinesPharmacist-verified orderDelivered across India

Key details

Salt: Empagliflozin (12.5mg) + Metformin (500mg)
Available variants: tablet tablet 10`S
Best price: ₹183 (₹18.28 per tablet)
Prescription: Required
Manufacturer: LUPIN LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

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Gibtulio Met XR 25/1000 mg Tablet

tablet - 10 S

₹183

₹18.28 per tablet

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Gibtulio Met XR 25/1000 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Gibtulio Met XR 25/1000 mg Tablet

Gibtulio Met XR 25/1000 mg Tablet contains Empagliflozin (12.5mg) + Metformin (500mg).

Uses of Gibtulio Met XR 25/1000 mg Tablet

Treatment of Type 2 diabetes mellitus

Key benefits

  • In Treatment of Type 2 diabetes mellitus Gibtulio Met 12.5mg/500mg Tablet is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level
  • you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage
  • eye damage
  • nerve problems and loss of limbs. This medicine will reduce the risk of dying from cardiovascular disease if you have type 2 diabetes and already have cardiovascular disease. Taking this medicine regularly along with proper diet and exercise will help you live a normal
  • healthy life. You should keep using it for as long as it is prescribed because it is protecting your future health.

How Gibtulio Met XR 25/1000 mg Tablet works

Gibtulio Met 12.5mg/500mg Tablet is a combination of two antidiabetic medicines: Empagliflozin and Metformin. Empagliflozin works by removing excess glucose from your body through urine. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Together, they lower blood glucose more effectively.

How to take Gibtulio Met XR 25/1000 mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gibtulio Met 12.5mg/500mg Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Gibtulio Met 12.5mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

Taking more Gibtulio Met XR 25/1000 mg than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Gibtulio Met XR 25/1000 mg Tablet

Most side effects of Gibtulio Met XR 25/1000 mg are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Gibtulio Met XR 25/1000 mg Tablet

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding UNSAFE
AlcoholAlcohol UNSAFE
DrivingDriving CONSULT YOUR DOCTOR
KidneyKidney UNSAFE
LiverLiver UNSAFE
Habit formingNo

Interactions with other medicines

Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Gibtulio Met XR 25/1000 mg. Some combinations can change how Gibtulio Met XR 25/1000 mg works or raise the chance of side effects.

How to store Gibtulio Met XR 25/1000 mg Tablet

Store Gibtulio Met XR 25/1000 mg below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the pack tightly closed and out of the reach of children. Do not use it after the expiry date printed on the pack.

Expert advice for Gibtulio Met XR 25/1000 mg Tablet

You have been prescribed this combination medicine as it can control blood sugar better than metformin alone. It also reduces the risk of heart attack, heart failure or other cardiovascular events. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines (if prescribed) along with Gibtulio Met 12.5mg/500mg Tablet. Take it with food to lower your chance of having an upset stomach. Practice good genital hygiene to prevent yeast or urinary tract infections It may cause your body to lose too much fluid (dehydration) or you to urinate more often. Drink plenty of water and stay hydrated. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Monitor your blood sugar level regularly. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
ANTI DIABETIC

Substitutes for Gibtulio Met XR 25/1000 mg Tablet

Medicines with the same active ingredient (Empagliflozin (12.5mg) + Metformin (500mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Gibtulio Met XR 25/1000 mg Tablet
Empagreat-M 500 mg TabletMANKIND (PHARMA)tablet · 10`S₹7261% cheaper
Empadus-M TabletLIVIDUS PHARMACEUTICALS PVT LTD.`tablet · 10`S₹7559% cheaper
Gluciemp-M 12.5/500 mg TabletHEAL (INDIA) PHARMACEUTICALStablet · 10`S₹10244% cheaper
Empanorm M 12.5/500 mg TabletALKEM LABtablet · 10`S₹11239% cheaper
Empacip M-XR 12.5/1000 mg TabletCIPLA LIMITEDtablet · 10`S₹14123% cheaper
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Gibtulio Met XR 25/1000 mg Tablet FAQs

What is Gibtulio Met XR 25/1000 mg Tablet used for?
Gibtulio Met XR 25/1000 mg Tablet is commonly used for Treatment of Type 2 diabetes mellitus. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Gibtulio Met XR 25/1000 mg Tablet?
Gibtulio Met XR 25/1000 mg Tablet contains Empagliflozin (12.5mg) + Metformin (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Gibtulio Met XR 25/1000 mg Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Gibtulio Met XR 25/1000 mg Tablet work?
Gibtulio Met 12.5mg/500mg Tablet is a combination of two antidiabetic medicines: Empagliflozin and Metformin.
Is Gibtulio Met XR 25/1000 mg Tablet a prescription medicine?
Yes. Gibtulio Met XR 25/1000 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Gibtulio Met XR 25/1000 mg Tablet?
The side effects reported most often with Gibtulio Met XR 25/1000 mg are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Gibtulio Met XR 25/1000 mg Tablet be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Gibtulio Met XR 25/1000 mg.
Can I drink alcohol while taking Gibtulio Met XR 25/1000 mg Tablet?
Alcohol UNSAFE
What if I miss a dose of Gibtulio Met XR 25/1000 mg Tablet?
If you miss a dose of Gibtulio Met 12.5mg/500mg Tablet, take it as soon as possible.
Is Gibtulio Met XR 25/1000 mg Tablet habit forming?
No. Gibtulio Met XR 25/1000 mg Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Gibtulio Met XR 25/1000 mg Tablet?
Empagreat-M 500 mg Tablet has the same active ingredient and strength and is listed from ₹72 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Gibtulio Met XR 25/1000 mg Tablet cost on PingMeDoc Pharmacy?
Gibtulio Met XR 25/1000 mg Tablet starts at ₹183 on PingMeDoc Pharmacy. Available in tablet tablet 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Gibtulio Met XR 25/1000 mg Tablet?
Gibtulio Met XR 25/1000 mg Tablet is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Gibtulio Met XR 25/1000 mg Tablet delivered?
Gibtulio Met XR 25/1000 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Gibtulio Met XR 25/1000 mg Tablet, Quick facts

Salt
Empagliflozin (12.5mg) + Metformin (500mg)
Form
tablet
Best price
₹183 (₹18.28 per tablet)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
ANTI DIABETIC
Habit forming
No
Variants
tablet tablet 10`S
Delivery
Standard across India

References

The information on Gibtulio Met XR 25/1000 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  2. National List of Essential Medicines (NLEM) 2022, Government of India.
  3. Manufacturer's package insert / prescribing information for Gibtulio Met XR 25/1000 mg Tablet.
  4. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

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Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.