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Prescription requiredGlimepiride (2mg) + Metformin (500mg) + Sitagliptin (50mg)

Istamet G IR 50/500/2 Tablet, Substitutes & Alternatives

Find medicines with the same composition as Istamet G IR 50/500/2 Tablet (Glimepiride (2mg) + Metformin (500mg) + Sitagliptin (50mg)). Compare alternatives at different price points.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

₹134MRP ₹14910% offIn stock
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Delivered across India, usually 8–11 days after the order is confirmed. ₹49 delivery, free above ₹999.

Cash on delivery available — pay when your order arrives

This medicine needs a prescription.

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A doctor decides whether a prescription can be issued. If it is not issued, the prescription items in your order are cancelled and refunded. You choose this at checkout.

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Known Substitutes

The following medicines may be used as alternatives to Istamet G IR 50/500/2 Tablet (same or similar composition):

  • Adipride SM2 Tablet
  • Glipisit GM 2/500 Tablet
  • Glisen SM 2/50/500 Tablet
  • Incresit GM 2 Tablet
  • Glyoka SM 2 Tablet
  • Istaprex GM 2 Tablet
  • Sugaray GM 50/2/500 Tablet
  • Sigadax GM 50/2/500 Tablet

Important: Never switch medicines without consulting your doctor or pharmacist. Even medicines with the same composition may have different inactive ingredients that affect how they work for you.

Understanding the Composition

Istamet G IR 50/500/2 Tablet contains Glimepiride (2mg) + Metformin (500mg) + Sitagliptin (50mg). Substitute medicines with the same active ingredient work by the same mechanism and treat the same conditions.

Price differences between brands are common and do not indicate a difference in quality or effectiveness. All medicines sold in India must meet the standards set by CDSCO (Central Drugs Standard Control Organisation).

Available Alternatives on PingMeDoc™

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Gemer Sita Ir 50/500/1MG Tab
5% offRx

Gemer Sita Ir 50/500/1MG Tab

Sun Pharma - Tablet - 50mg + 2mg + 500mg - 10 S

₹137.75₹145

Save ₹7.25

Prescription required

5% offRx

Glimiprime Sm2 Tab

Primus Pharma - Tablet - 2mg + 500mg + 50mg - 10 S

₹138.35₹145.63

Save ₹7.28

Prescription required

Istamet G-Ir 50/500/2MG Tab
5% offRx

Istamet G-Ir 50/500/2MG Tab

Sun Pharma - Tablet - 2mg + 500mg + 50mg - 10 S

₹145.17₹152.81

Save ₹7.64

Prescription required

Glisen Sm 2/50/500MG Tab
5% offRx

Glisen Sm 2/50/500MG Tab

Alembic Pharma - Tablet - 2mg + 500mg + 50mg - 10 S

₹149.15₹157

Save ₹7.85

Prescription required

Gluconorm-Gs 2MG Tab
5% offRx

Gluconorm-Gs 2MG Tab

Lupin Lab - Tablet - 2 mg - 10 S

₹160.65₹169.10

Save ₹8.45

Prescription required

Istamet G IR 50/500/2 Tablet: At a Glance

Composition
Glimepiride (2mg) + Metformin (500mg) + Sitagliptin (50mg)
Price
₹134
Prescription
Required (Rx)
Manufacturer
Sun Pharma Laboratories Ltd
Known substitutes
8

Istamet G IR 50/500/2 Tablet: Substitute FAQs

Are substitutes as effective as the original medicine?
Substitutes with the same active ingredient (salt) work in a similar way. However, inactive ingredients may differ. Always consult your doctor before switching.
Why are some substitutes cheaper?
Generic medicines are usually cheaper because manufacturers don't have the same development costs as the original brand. They contain the same active ingredient in the same strength.
Can I switch to a substitute on my own?
No. Always consult your doctor or pharmacist before switching medicines, even if the substitute has the same composition.
What is the difference between generic and branded medicines?
Generic medicines contain the same active ingredients as branded ones but are sold under different names, often at lower prices. Both are regulated for safety and efficacy.

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Safety disclaimer

Never switch medicines without consulting your doctor. This page is for educational purposes only. Individual response to medicines may vary.