Jubira 10 mg Tablet

Composition of Jubira 10 mg Tablet

Jubira 10 mg Tablet contains Tofacitinib 10 mg. It belongs to the Janus kinase (JAK) inhibitor class of medicines.

Uses of Jubira 10 mg Tablet

• Treatment of rheumatoid arthritis
• psoriatic arthritis
• ulcerative colitis (in appropriate patients as prescribed); sometimes used for other autoimmune/inflammatory conditions on specialist advice

Key benefits

• Reduces joint pain and swelling in inflammatory arthritis
• Helps achieve/maintain remission in ulcerative colitis
• Improves physical function and quality of life
• Lowers inflammatory activity in autoimmune disease

How Jubira 10 mg Tablet works

Tofacitinib is a Janus kinase (JAK) inhibitor. It blocks JAK-mediated signaling pathways involved in inflammation, thereby reducing immune overactivity and symptoms such as pain, swelling and bowel inflammation.

How to take Jubira 10 mg Tablet

Tablet for oral use. Take exactly as prescribed by the doctor, at the same time each day, with or without food. Do not crush/chew unless advised; do not stop abruptly without medical advice. Regular blood tests may be required.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Jubira 10 mg Tablet

Most side effects of Jubira are mild and settle as the body adjusts. Reported side effects include:

• Upper respiratory tract infection
• headache
• diarrhea
• nausea
• increased cholesterol
• elevated liver enzymes
• herpes zoster (shingles)
• hypertension

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Jubira 10 mg Tablet

Warnings and precautions

Prescription-only immunosuppressant. Increases risk of serious infections (TB, fungal, viral), shingles; screen for TB/hepatitis before starting. May increase risk of blood clots (DVT/PE), major cardiovascular events, and certain cancers; use lowest effective dose and avoid/use extreme caution in high-risk patients (history of clots, smokers, cardiovascular disease). Monitor CBC, LFT, lipids; risk of low blood counts. Avoid live vaccines during therapy. Use caution in liver/kidney impairment; dose adjustments may be needed. Seek urgent care for fever, persistent cough, chest pain, shortness of breath, leg swelling, or unusual bleeding/bruising.

Do not take Jubira if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Strong CYP3A4 inhibitors (ketoconazole, clarithromycin) may increase levels; strong CYP3A4 inducers (rifampicin, carbamazepine, phenytoin, St John’s wort) may reduce effect; immunosuppressants/biologics (azathioprine, cyclosporine, tacrolimus, TNF inhibitors) increase infection risk and are generally avoided; live vaccines; caution with other drugs increasing clot risk

How to store Jubira 10 mg Tablet

Store below 25°C, in a dry place, protected from light and moisture. Keep in original pack and out of reach of children.

Expert advice for Jubira 10 mg Tablet

Keep every monitoring blood test appointment. Carry a note of the medicine and its schedule, especially for weekly dosing.

Manufacturer and class

Manufacturer:

JUBILANT LIFESCIENCES

Therapeutic class:

Immunosuppressant / Anti-rheumatic

Drug class:

Janus kinase (JAK) inhibitor