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Prescription requiredKlm LabAnti-acne agent and Antibiotic

Nioclean-Ad

Adapalene + Clindamycin

₹210MRP ₹222In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Nioclean-Ad is used for this medicine is used in the treatment of acne, blackheads and whiteheads, pigmentation, rough skin, bacterial infection, gut infection, skin infection and dental infection.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Adapalene + Clindamycin
Available variants: NA 15GM
Best price: ₹210 (₹14.03 per g)
MRP: ₹222
Prescription: Required
Manufacturer: KLM LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Nioclean-Ad

Nioclean-Ad contains Adapalene + Clindamycin. It belongs to the Retinoid / keratolytic and Antibacterial agent class of medicines.

Uses of Nioclean-Ad

  • This medicine is used in the treatment of acne
  • blackheads and whiteheads
  • pigmentation
  • rough skin
  • bacterial infection
  • gut infection
  • skin infection and dental infection.

Key benefits

  • Clears and prevents acne
  • Improves skin texture and marks over time
  • Targets infections that other antibiotic groups do not reach

How Nioclean-Ad works

This medicine combines 2 active ingredients: Adapalene and Clindamycin. Adapalene unblocks the pores and speeds up the turnover of skin cells, so fewer spots form. Clindamycin kills or stops the growth of the bacteria causing your infection.

How to take Nioclean-Ad

Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. It can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Nioclean-Ad

Most side effects of Nioclean-Ad are mild and settle as the body adjusts. Reported side effects include:

  • Dryness
  • Peeling
  • Redness
  • Burning or stinging
  • Increased sensitivity to sunlight
  • Nausea
  • Metallic taste
  • Loose motions
  • Stomach pain
  • Headache

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Nioclean-Ad

PregnancyNot recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant.
BreastfeedingNot recommended while breastfeeding.
AlcoholDo not drink alcohol while taking this medicine.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyConsult your doctor if you have kidney disease.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds. Finish the whole course even after you feel better. Do not drink any alcohol while taking metronidazole, ornidazole or tinidazole, or for the period after the course that your doctor states — the combination causes severe flushing, vomiting and a racing heart. Report severe or watery loose motions during or after the course rather than treating them yourself. Tetracyclines stain developing teeth and are avoided in young children and in pregnancy. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses.

Do not take Nioclean-Ad if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.

Interactions with other medicines

Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics. Antacids, iron, zinc and calcium reduce the absorption of tetracyclines — separate them by a couple of hours. Tell your doctor if you take a blood thinner.

How to store Nioclean-Ad

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Nioclean-Ad

Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars. Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness.

Manufacturer and class

Manufacturer:
KLM LAB
Therapeutic class:
Anti-acne agent and Antibiotic
Drug class:
Retinoid / keratolytic and Antibacterial agent

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Nioclean-Ad FAQs

What is Nioclean-Ad used for?
Nioclean-Ad is commonly used for This medicine is used in the treatment of acne, blackheads and whiteheads, pigmentation, rough skin, bacterial infection, gut infection, skin infection and dental infection. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Nioclean-Ad?
Nioclean-Ad contains Adapalene + Clindamycin. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Nioclean-Ad?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Nioclean-Ad work?
This medicine combines 2 active ingredients: Adapalene and Clindamycin.
Is Nioclean-Ad a prescription medicine?
Yes. Nioclean-Ad is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Nioclean-Ad?
The side effects reported most often with Nioclean-Ad are Dryness, Peeling, Redness, Burning or stinging, Increased sensitivity to sunlight. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Nioclean-Ad be taken during pregnancy?
Not recommended in pregnancy — it may harm the developing baby. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Nioclean-Ad.
Can I drink alcohol while taking Nioclean-Ad?
Do not drink alcohol while taking this medicine.
What if I miss a dose of Nioclean-Ad?
Take it as soon as you remember.
Is Nioclean-Ad habit forming?
No. Nioclean-Ad is not known to be habit forming when taken as prescribed.
How much does Nioclean-Ad cost on PingMeDoc Pharmacy?
Nioclean-Ad starts at ₹210 (MRP ₹222) on PingMeDoc Pharmacy. Available in NA 15GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Nioclean-Ad?
Nioclean-Ad is manufactured by KLM LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Nioclean-Ad delivered?
Nioclean-Ad is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Nioclean-Ad, Quick facts

Salt
Adapalene + Clindamycin
Best price
₹210 (₹14.03 per g)
MRP
₹222
Prescription
Required (Rx)
Brand
KLM LAB
Manufacturer
KLM LAB
Therapeutic class
Anti-acne agent and Antibiotic
Drug class
Retinoid / keratolytic and Antibacterial agent
Habit forming
No
Variants
NA 15GM
Delivery
Standard across India

References

The information on Nioclean-Ad is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Nioclean-Ad.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.