Peramnel 4 Tablet

Composition of Peramnel 4 Tablet

Peramnel 4 Tablet contains Perampanel (4mg). It belongs to the Anticonvulsant class of medicines.

Uses of Peramnel 4 Tablet

Epilepsy/Seizures

Key benefits

• In Epilepsy/Seizures Peramnel 4 Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion
• uncontrollable jerking movements
• loss of awareness
• and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well until your doctor advises you to. Missing doses may trigger a seizure.

How Peramnel 4 Tablet works

Peramnel 4 Tablet is an antiepileptic medication. It prevents seizures in patients with epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.

How to take Peramnel 4 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Peramnel 4 Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Peramnel 4 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause deep unconsciousness, slowed breathing and dangerous heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Peramnel 4 Tablet

Most side effects of Peramnel are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Peramnel 4 Tablet

Warnings and precautions

Never stop or change an anti-epileptic on your own. Stopping abruptly can cause prolonged, dangerous seizures. Sodium valproate and divalproex must not be used by anyone who is pregnant or could become pregnant unless a specialist has confirmed there is no alternative — they cause serious birth defects and developmental problems. Effective contraception is essential. Seek urgent care for any rash, especially in the first weeks — a rash with fever, blistering or peeling can be life-threatening. Report yellowing of the eyes or skin, persistent vomiting, unusual bruising or severe tiredness at once. Tell your doctor about any change in mood or any thoughts of harming yourself. Take the same brand each time unless your neurologist has agreed to a change; switching can alter seizure control.

Do not take Peramnel if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Valproate-containing medicines are contraindicated in pregnancy for epilepsy unless no alternative exists, and in all women of childbearing potential without a pregnancy prevention programme. Several are not suitable in significant liver disease.

Interactions with other medicines

This group interacts very widely, including with contraceptives, blood thinners and other anti-epileptics. Give your doctor a full list of what you take. Hormonal contraception may become unreliable — ask your doctor which method to use.

How to store Peramnel 4 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Peramnel 4 Tablet

Take your medication regularly as directed by your doctor as missing doses can trigger seizures. Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you. Some healthy tips to prevent seizures: Take a healthy diet along with regular exercise. Practice yoga every day. Get enough sleep at nighttime. Limit the use of screen time such as mobile/ laptop. Take your medication on time. Do not drive or do anything that requires mental focus until you know how Peramnel 4 Tablet affects you. It may cause weight gain. Hence, monitor your weight regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior. Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Manufacturer and class

Manufacturer:

ICON PHARMA

Therapeutic class:

NEURO CNS

Drug class:

Anticonvulsant

Chemical class:

Bipyridines and oligopyridines