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Skn Organics (P) Ltd. - Tablet - 200mg + 20mg - 10 S
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Metronidazole (1%w/w) + Povidone Iodine (5%w/w)
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Plus + Ointment is used for plus Ointment is used in the treatment of wound infection.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Plus + Ointment contains Metronidazole (1%w/w) + Povidone Iodine (5%w/w). It belongs to the Antibacterial agent and Antiseptic and disinfectant class of medicines.
Plus Ointment is used in the treatment of wound infection.
Plus Ointment is a combination of two medicines: Metronidazole and Povidone Iodine. Metronidazole is an antibiotic which kills bacteria and other harmful microorganisms by damaging their DNA. Povidone Iodine is an antiseptic applied on skin which is infected or is likely to get infected. It slowly releases iodine which kills or prevents the growth of these microorganisms.
Clean and dry the affected area, then apply a thin layer and rub it in gently. Wash your hands before and after use, unless your hands are the area being treated. This is for use on the skin only — do not swallow it. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. It is unlikely from skin use, but swallowing an antiseptic is dangerous and needs immediate medical attention. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Plus + are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Plus Ointment may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Plus Ointment should be used with caution during lactation. Breast feeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.<br>If a single dose of Plus Ointment is used, it is recommended to hold breastfeeding for 12-24 hours to allow the removal of the drug. |
| Alcohol | Do not drink alcohol while taking this medicine. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Finish the whole course even after you feel better. Do not drink any alcohol while taking metronidazole, ornidazole or tinidazole, or for the period after the course that your doctor states — the combination causes severe flushing, vomiting and a racing heart. Report severe or watery loose motions during or after the course rather than treating them yourself. Tetracyclines stain developing teeth and are avoided in young children and in pregnancy. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses. For external use only. Keep away from the eyes and the inside of the mouth and nose unless the product is made for that purpose. Do not use a strong antiseptic repeatedly on an open wound — clean running water and soap around the edges are usually better, and harsh antiseptics slow healing. See a doctor for a deep or dirty wound, an animal bite, a wound that will not stop bleeding, or one that becomes red, swollen, warm or discharges. Check that your tetanus cover is current after any dirty or penetrating wound.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for use on large burns or deep wounds without medical advice.
Antacids, iron, zinc and calcium reduce the absorption of tetracyclines — separate them by a couple of hours. Tell your doctor if you take a blood thinner. No significant interactions are expected.
Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.
Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness. Clean the wound under running water first, then apply. Cover a clean wound with a sterile dressing and change it if it becomes wet or dirty.

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The information on Plus + Ointment is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.