Acuclav 375
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Prescription required
Prescription requiredMacleods Pharmaceuticals Pvt LtdAntibiotic
Polyclav DS 457 mg
Amoxycillin + Clavulanic Acid
₹172MRP ₹181In stock
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Polyclav DS 457 mg is used for this medicine is used in the treatment of bacterial infection, throat infection, chest infection, skin infection and urinary infection.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Amoxycillin + Clavulanic Acid
Available variants: 457 mg 30ML
Best price: ₹172 (₹5.75 per ml)
MRP: ₹181
Prescription: Required
Manufacturer: MACLEODS PHARMACEUTICALS LTD
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Polyclav DS 457 mg
Polyclav DS 457 mg contains Amoxycillin + Clavulanic Acid. It belongs to the Penicillin class of medicines.
Uses of Polyclav DS 457 mg
- This medicine is used in the treatment of bacterial infection
- throat infection
- chest infection
- skin infection and urinary infection.
Key benefits
- Long-established and effective
- Works against a wide range of common infections
How Polyclav DS 457 mg works
This medicine combines 2 active ingredients: Amoxycillin and Clavulanic Acid. Amoxycillin kills the bacteria causing your infection by breaking down the wall they need to survive. Clavulanic Acid kills the bacteria causing your infection by breaking down the wall they need to survive.
How to take Polyclav DS 457 mg
Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause vomiting, severe loose motions and, rarely, fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Polyclav DS 457 mg
Most side effects of Polyclav DS are mild and settle as the body adjusts. Reported side effects include:
- Loose motions
- Nausea
- Rash
- Vomiting
- Thrush
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Polyclav DS 457 mg
| Pregnancy | Consult your doctor before using this in pregnancy. |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Alcohol may worsen the side effects of this medicine. Limit it. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Warnings and precautions
Finish the whole course even after you feel better. Stopping early lets the strongest bacteria survive, and they are the ones that come back resistant. Stop and seek emergency care for swelling of the face or throat, difficulty breathing, or a widespread rash — a penicillin allergy can be serious. Tell every doctor and pharmacist if you have ever reacted to penicillin. Tell your doctor if loose motions become severe or watery, or continue after the course — this needs attention rather than an anti-diarrhoeal. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses.
Do not take Polyclav DS if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known penicillin allergy.
Interactions with other medicines
May reduce the reliability of the oral contraceptive pill if you have vomiting or loose motions — use additional precautions during the course. Tell your doctor if you take methotrexate or a blood thinner.
How to store Polyclav DS 457 mg
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Expert advice for Polyclav DS 457 mg
Space the doses evenly through the day so the level stays steady. Take a probiotic a few hours apart if loose motions trouble you, and drink plenty of fluids. Never use a leftover antibiotic, or someone else's, for a new illness.
Manufacturer and class
- Manufacturer:
- MACLEODS PHARMACEUTICALS LTD
- Therapeutic class:
- Antibiotic
- Drug class:
- Penicillin
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Polyclav DS 457 mg FAQs
What is Polyclav DS 457 mg used for?
Polyclav DS 457 mg is commonly used for This medicine is used in the treatment of bacterial infection, throat infection, chest infection, skin infection and urinary infection. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Polyclav DS 457 mg?
Polyclav DS 457 mg contains Amoxycillin + Clavulanic Acid. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Polyclav DS 457 mg?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Polyclav DS 457 mg work?
This medicine combines 2 active ingredients: Amoxycillin and Clavulanic Acid.
Is Polyclav DS 457 mg a prescription medicine?
Yes. Polyclav DS 457 mg is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Polyclav DS 457 mg?
The side effects reported most often with Polyclav DS are Loose motions, Nausea, Rash, Vomiting, Thrush. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Polyclav DS 457 mg be taken during pregnancy?
Consult your doctor before using this in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Polyclav DS.
Can I drink alcohol while taking Polyclav DS 457 mg?
Alcohol may worsen the side effects of this medicine.
What if I miss a dose of Polyclav DS 457 mg?
Take it as soon as you remember.
Is Polyclav DS 457 mg habit forming?
No. Polyclav DS 457 mg is not known to be habit forming when taken as prescribed.
How much does Polyclav DS 457 mg cost on PingMeDoc Pharmacy?
Polyclav DS 457 mg starts at ₹172 (MRP ₹181) on PingMeDoc Pharmacy. Available in 457 mg 30ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Polyclav DS 457 mg?
Polyclav DS 457 mg is manufactured by MACLEODS PHARMACEUTICALS LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Polyclav DS 457 mg delivered?
Polyclav DS 457 mg is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Polyclav DS 457 mg, Quick facts
- Salt
- Amoxycillin + Clavulanic Acid
- Best price
- ₹172 (₹5.75 per ml)
- MRP
- ₹181
- Prescription
- Required (Rx)
- Brand
- Macleods Pharmaceuticals Pvt Ltd
- Manufacturer
- MACLEODS PHARMACEUTICALS LTD
- Therapeutic class
- Antibiotic
- Drug class
- Penicillin
- Habit forming
- No
- Variants
- 457 mg 30ML
- Delivery
- Standard across India
References
The information on Polyclav DS 457 mg is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Polyclav DS 457 mg.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.