
Adrole 0.5
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Pregabalin 200 mg + Nortriptyline 10 mg (tablet)
Available at our pharmacy counter
This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.
In-store reference price ₹147
Progaba Nt 200 Tablet is used for neuropathic (nerve) pain such as diabetic neuropathy, post-herpetic neuralgia; nerve pain associated with radiculopathy/sciatica; pain with tingling, burning, numbness.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Progaba Nt 200 Tablet contains Pregabalin 200 mg + Nortriptyline 10 mg (tablet). It belongs to the Gabapentinoid + Tricyclic antidepressant (TCA) class of medicines.
Pregabalin reduces release of pain-signaling neurotransmitters by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the nervous system. Nortriptyline increases noradrenaline/serotonin activity and modulates pain pathways, improving neuropathic pain symptoms.
Take by mouth exactly as prescribed, usually once daily at bedtime (may cause drowsiness). Can be taken with or without food; swallow whole with water. Do not stop abruptly—doctor may taper dose.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. It can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Progaba Nt are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Use with caution / Consult doctor |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
May cause dizziness and sleepiness—avoid driving/operating machinery until you know the effect. Use caution in elderly and in kidney disease (dose adjustment needed for pregabalin). Nortriptyline can cause constipation, urinary retention, and may worsen glaucoma/prostatic enlargement; caution in heart disease/arrhythmias. Do not stop suddenly (withdrawal symptoms). Monitor for mood changes/suicidal thoughts. Seek urgent care for facial swelling, severe rash, breathing difficulty (allergy/angioedema).
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Alcohol and other CNS depressants (opioids, benzodiazepines, sedating antihistamines) increase drowsiness/respiratory depression risk; MAO inhibitors (contraindicated with nortriptyline); SSRIs/SNRIs and other serotonergic drugs (serotonin syndrome risk); other tricyclics/anticholinergics (additive side effects); QT-prolonging drugs (arrhythmia risk); strong CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine) may increase nortriptyline levels.
Store at room temperature (below 25°C), protected from moisture and light. Keep in original strip and out of reach of children.
Take the larger part of the dose at night if drowsiness is a problem. Rise slowly from sitting or lying, especially in the first weeks. Keep your review appointment so the dose can be adjusted to the lowest that controls your pain. Give it a fair trial of several weeks, and keep your review appointments. Take it at the same time each day — at night if it makes you drowsy, in the morning if it disturbs sleep. Talking therapy alongside medicine works better than either alone for most people.

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.