Progaba Nt 200 Tablet

Composition of Progaba Nt 200 Tablet

Progaba Nt 200 Tablet contains Pregabalin 200 mg + Nortriptyline 10 mg (tablet). It belongs to the Gabapentinoid + Tricyclic antidepressant (TCA) class of medicines.

Uses of Progaba Nt 200 Tablet

• Neuropathic (nerve) pain such as diabetic neuropathy
• post-herpetic neuralgia; nerve pain associated with radiculopathy/sciatica; pain with tingling
• burning
• numbness.

Key benefits

• Relieves burning/tingling nerve pain
• Reduces shooting/electric shock-like pain
• Improves sleep disturbed by neuropathic pain
• Helps numbness and paresthesia
• Improves daily functioning in chronic nerve pain

How Progaba Nt 200 Tablet works

Pregabalin reduces release of pain-signaling neurotransmitters by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the nervous system. Nortriptyline increases noradrenaline/serotonin activity and modulates pain pathways, improving neuropathic pain symptoms.

How to take Progaba Nt 200 Tablet

Take by mouth exactly as prescribed, usually once daily at bedtime (may cause drowsiness). Can be taken with or without food; swallow whole with water. Do not stop abruptly—doctor may taper dose.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Progaba Nt as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Progaba Nt than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Progaba Nt 200 Tablet

Most side effects of Progaba Nt are mild and settle as the body adjusts. Reported side effects include:

• Dizziness
• sleepiness/drowsiness
• dry mouth
• constipation
• blurred vision
• weight gain
• swelling of legs/feet (edema)
• fatigue
• difficulty concentrating

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Progaba Nt 200 Tablet

Warnings and precautions

May cause dizziness and sleepiness—avoid driving/operating machinery until you know the effect. Use caution in elderly and in kidney disease (dose adjustment needed for pregabalin). Nortriptyline can cause constipation, urinary retention, and may worsen glaucoma/prostatic enlargement; caution in heart disease/arrhythmias. Do not stop suddenly (withdrawal symptoms). Monitor for mood changes/suicidal thoughts. Seek urgent care for facial swelling, severe rash, breathing difficulty (allergy/angioedema).

Interactions with other medicines

Alcohol and other CNS depressants (opioids, benzodiazepines, sedating antihistamines) increase drowsiness/respiratory depression risk; MAO inhibitors (contraindicated with nortriptyline); SSRIs/SNRIs and other serotonergic drugs (serotonin syndrome risk); other tricyclics/anticholinergics (additive side effects); QT-prolonging drugs (arrhythmia risk); strong CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine) may increase nortriptyline levels.

How to store Progaba Nt 200 Tablet

Store at room temperature (below 25°C), protected from moisture and light. Keep in original strip and out of reach of children.

Manufacturer and class

Manufacturer:

ICON PHARMA

Therapeutic class:

Neuropathic pain agent (analgesic/adjuvant)

Drug class:

Gabapentinoid + Tricyclic antidepressant (TCA)