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Prescription requiredLupin LabPAIN ANALGESICS

Signoheal DS Tablet

Bromelain (180mg) + Trypsin (96mg) + Rutoside (200mg)

Signoheal DS Tablet is used for pain relief.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹281₹28.13 per tablet
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Bromelain (180mg) + Trypsin (96mg) + Rutoside (200mg)
Available variants: tablet tablet 10`S
Best price: ₹281 (₹28.13 per tablet)
Prescription: Required
Manufacturer: LUPIN LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Signoheal DS Tablet

Signoheal DS Tablet contains Bromelain (180mg) + Trypsin (96mg) + Rutoside (200mg). It belongs to the Enzyme / disease-modifying anti-rheumatic agent class of medicines.

Uses of Signoheal DS Tablet

Pain relief

Key benefits

  • In Pain relief Signoheal DS Tablet is a combination of medicines used for relief of pain
  • inflammation
  • and swelling in conditions that may occur due to trauma
  • surgery or everyday life. It may also be used to provide relief in degenerative and inflammatory conditions that affect muscles and joints such as rheumatoid arthritis and osteoarthritis. It promotes speedy recovery due to its anti-inflammatory and antioxidant properties. Take it as it is prescribed to get the most benefit. This will help you to go about your daily activities more easily and have a better
  • more active
  • quality of life.

How Signoheal DS Tablet works

Signoheal DS Tablet is a combination of two enzymes (Bromelain, Trypsin) and an antioxidant (Rutoside). The enzymes work by increasing the blood supply to the affected area and helping the body produce substances that fight pain and swelling. The antioxidant protects the body from damage by chemicals (free radicals) and further reduces swelling.

How to take Signoheal DS Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Signoheal DS Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Signoheal DS Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Signoheal DS Tablet

Most side effects of Signoheal DS are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Signoheal DS Tablet

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving CONSULT YOUR DOCTOR
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.

Do not take Signoheal DS if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.

How to store Signoheal DS Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Signoheal DS Tablet

Take it with plenty of fluids, an hour before or two hours after a meal. It may increase the severity of your condition at the start of treatment. Continue using it as prescribed by your doctor. It may cause dizziness and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you. It may change the color, consistency, and odor of your stool. This is harmless. Inform your doctor if this bothers you.

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
PAIN ANALGESICS
Drug class:
Enzyme / disease-modifying anti-rheumatic agent

Substitutes for Signoheal DS Tablet

Medicines with the same active ingredient (Bromelain (180mg) + Trypsin (96mg) + Rutoside (200mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Signoheal DS Tablet
Disencher TabletROUCHER BIOSCIENCES PVT LTDtablet · 10`S₹634125% more
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Signoheal DS Tablet FAQs

What is Signoheal DS Tablet used for?
Signoheal DS Tablet is commonly used for Pain relief. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Signoheal DS Tablet?
Signoheal DS Tablet contains Bromelain (180mg) + Trypsin (96mg) + Rutoside (200mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Signoheal DS Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Signoheal DS Tablet work?
Signoheal DS Tablet is a combination of two enzymes (Bromelain, Trypsin) and an antioxidant (Rutoside).
Is Signoheal DS Tablet a prescription medicine?
Yes. Signoheal DS Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Signoheal DS Tablet?
The side effects reported most often with Signoheal DS are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Signoheal DS Tablet be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Signoheal DS.
Can I drink alcohol while taking Signoheal DS Tablet?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Signoheal DS Tablet?
If you miss a dose of Signoheal DS Tablet, take it as soon as possible.
Is Signoheal DS Tablet habit forming?
No. Signoheal DS Tablet is not known to be habit forming when taken as prescribed.
How much does Signoheal DS Tablet cost on PingMeDoc Pharmacy?
Signoheal DS Tablet starts at ₹281 on PingMeDoc Pharmacy. Available in tablet tablet 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Signoheal DS Tablet?
Signoheal DS Tablet is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Signoheal DS Tablet delivered?
Signoheal DS Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Signoheal DS Tablet, Quick facts

Salt
Bromelain (180mg) + Trypsin (96mg) + Rutoside (200mg)
Form
tablet
Best price
₹281 (₹28.13 per tablet)
Prescription
Required (Rx)
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
PAIN ANALGESICS
Drug class
Enzyme / disease-modifying anti-rheumatic agent
Habit forming
No
Variants
tablet tablet 10`S
Delivery
Standard across India

References

The information on Signoheal DS Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Signoheal DS Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.