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Prescription requiredEnzo PharmaTopical corticosteroid, Dermatological agent and Anti-acne agent

Twinkle Star Oil

Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

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Twinkle Star Oil is used for twinkle Cream is used in the treatment of melasma.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)
Available variants: oil NA 100ML
Best price: ₹123 (₹1.23 per ml)
MRP: ₹129
Prescription: Required
Manufacturer: ENZO PHARMA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Twinkle Star Oil

Twinkle Star Oil contains Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w). It belongs to the Corticosteroid / calcineurin inhibitor, Skin preparation and Retinoid / keratolytic class of medicines.

Uses of Twinkle Star Oil

Twinkle Cream is used in the treatment of melasma.

Key benefits

  • Rapid relief of itching and inflammation
  • Acts where it is applied
  • Clears and prevents acne
  • Improves skin texture and marks over time

How Twinkle Star Oil works

Twinkle Cream is a combination of three medicines: Hydroquinone, Mometasone and Tretinoin, which treats melasma (dark spots on skin). Hydroquinone is a skin lightening medicine. It reduces the amount of a skin pigment (melanin) that causes darkening of skin. This effect is reversible. Mometasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly.

How to take Twinkle Star Oil

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. It is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Twinkle Star Oil

Most side effects of Twinkle Star Oil are mild and settle as the body adjusts. Reported side effects include:

  • Application site reactions (burning
  • irritation
  • itching and redness)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Twinkle Star Oil

PregnancyTwinkle Cream may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingTwinkle Cream is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
AlcoholNo interaction found/established
DrivingNot expected to affect your ability to drive.
KidneyNo interaction found/established
LiverNo interaction found/established
Habit formingNo

Warnings and precautions

Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted. For external use only, unless the pack says otherwise. Stop if the skin becomes more irritated, and see a doctor if the condition worsens or spreads. Do a small test patch first if you have sensitive skin. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds.

Do not take Twinkle Star Oil if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes. Not for use on broken or infected skin unless prescribed. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.

Interactions with other medicines

No significant interactions are expected from preparations used on the skin. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.

How to store Twinkle Star Oil

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Twinkle Star Oil

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Twinkle Cream is used for the short-term treatment of mild to moderate melasma.</li> <li>It helps reduce scars, marks, blemishes, and dark circles under the eyes.</li> <li>It should always be used along with sun-avoidance measures, like using sunscreens and wearing protective clothing.</li> <li>Apply and massage gently till the cream is fully absorbed, once daily at night.</li> <li>Initial improvement may be seen in just 2 weeks, full results generally appear after 2-3 months of regular use.</li> <li>Do not apply on broken or infected areas of skin. Discontinue use if you experience irritation or allergy and consult your doctor.</li> <li>Do not use it for longer than 6-8 weeks without consulting your doctor.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
ENZO PHARMA
Therapeutic class:
Topical corticosteroid, Dermatological agent and Anti-acne agent
Drug class:
Corticosteroid / calcineurin inhibitor, Skin preparation and Retinoid / keratolytic

Substitutes for Twinkle Star Oil

Medicines with the same active ingredient (Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Twinkle Star Oil
Skinshine CreamCOMMON PRODUCTScream · 15 Gm₹1263% more
Elosone Ht Cream15G₹1285% more
Melazip CreamFIZIKS LIFE SCIENCEcream · 20GM₹14216% more
Decdan Lite CreamWockhardt Ltdcream · 15GM₹16938% more
Skinlite CreamZYDUS HEALTHCARE PHARMAcream · 15 Gm₹18954% more
Lomela CreamIntas Pharmaceuticals Ltdcream · 18GM₹20971% more
Hhlite CreamH & H PHARMACEUTICAL PVT LTDcream · 20GM₹249103% more
Metacortil LiteMacleods Pharmaceuticals Pvt Ltd15GM₹265117% more
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Twinkle Star Oil FAQs

What is Twinkle Star Oil used for?
Twinkle Star Oil is commonly used for Twinkle Cream is used in the treatment of melasma. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Twinkle Star Oil?
Twinkle Star Oil contains Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Twinkle Star Oil?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Twinkle Star Oil work?
Twinkle Cream is a combination of three medicines: Hydroquinone, Mometasone and Tretinoin, which treats melasma (dark spots on skin).
Is Twinkle Star Oil a prescription medicine?
Yes. Twinkle Star Oil is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Twinkle Star Oil?
The side effects reported most often with Twinkle Star Oil are Application site reactions (burning, irritation, itching and redness). Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Twinkle Star Oil be taken during pregnancy?
Twinkle Cream may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Twinkle Star Oil.
Can I drink alcohol while taking Twinkle Star Oil?
No interaction found/established
What if I miss a dose of Twinkle Star Oil?
Take it as soon as you remember.
Is Twinkle Star Oil habit forming?
No. Twinkle Star Oil is not known to be habit forming when taken as prescribed.
How much does Twinkle Star Oil cost on PingMeDoc Pharmacy?
Twinkle Star Oil starts at ₹123 (MRP ₹129) on PingMeDoc Pharmacy. Available in oil NA 100ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Twinkle Star Oil?
Twinkle Star Oil is manufactured by ENZO PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Twinkle Star Oil delivered?
Twinkle Star Oil is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Twinkle Star Oil, Quick facts

Salt
Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)
Form
oil
Best price
₹123 (₹1.23 per ml)
MRP
₹129
Prescription
Required (Rx)
Schedule
Schedule H
Brand
ENZO PHARMA
Manufacturer
ENZO PHARMA
Therapeutic class
Topical corticosteroid, Dermatological agent and Anti-acne agent
Drug class
Corticosteroid / calcineurin inhibitor, Skin preparation and Retinoid / keratolytic
Habit forming
No
Variants
oil NA 100ML
Delivery
Standard across India

References

The information on Twinkle Star Oil is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Twinkle Star Oil.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.