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Enzo Pharma - Tablet - 10 S
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Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Twinkle Star Oil is used for twinkle Cream is used in the treatment of melasma.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Twinkle Star Oil contains Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w). It belongs to the Corticosteroid / calcineurin inhibitor, Skin preparation and Retinoid / keratolytic class of medicines.
Twinkle Cream is used in the treatment of melasma.
Twinkle Cream is a combination of three medicines: Hydroquinone, Mometasone and Tretinoin, which treats melasma (dark spots on skin). Hydroquinone is a skin lightening medicine. It reduces the amount of a skin pigment (melanin) that causes darkening of skin. This effect is reversible. Mometasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. It is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Twinkle Star Oil are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Twinkle Cream may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Twinkle Cream is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable. |
| Alcohol | No interaction found/established |
| Driving | Not expected to affect your ability to drive. |
| Kidney | No interaction found/established |
| Liver | No interaction found/established |
| Habit forming | No |
Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted. For external use only, unless the pack says otherwise. Stop if the skin becomes more irritated, and see a doctor if the condition worsens or spreads. Do a small test patch first if you have sensitive skin. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes. Not for use on broken or infected skin unless prescribed. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.
No significant interactions are expected from preparations used on the skin. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Twinkle Cream is used for the short-term treatment of mild to moderate melasma.</li> <li>It helps reduce scars, marks, blemishes, and dark circles under the eyes.</li> <li>It should always be used along with sun-avoidance measures, like using sunscreens and wearing protective clothing.</li> <li>Apply and massage gently till the cream is fully absorbed, once daily at night.</li> <li>Initial improvement may be seen in just 2 weeks, full results generally appear after 2-3 months of regular use.</li> <li>Do not apply on broken or infected areas of skin. Discontinue use if you experience irritation or allergy and consult your doctor.</li> <li>Do not use it for longer than 6-8 weeks without consulting your doctor.</li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Mometasone (0.1%w/w) + Hydroquinone (2%w/w) + Tretinoin (0.025%w/w)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Twinkle Star Oil |
|---|---|---|---|
| Skinshine CreamCOMMON PRODUCTS | cream · 15 Gm | ₹126 | 3% more |
| Elosone Ht Cream | 15G | ₹128 | 5% more |
| Melazip CreamFIZIKS LIFE SCIENCE | cream · 20GM | ₹142 | 16% more |
| Decdan Lite CreamWockhardt Ltd | cream · 15GM | ₹169 | 38% more |
| Skinlite CreamZYDUS HEALTHCARE PHARMA | cream · 15 Gm | ₹189 | 54% more |
| Lomela CreamIntas Pharmaceuticals Ltd | cream · 18GM | ₹209 | 71% more |
| Hhlite CreamH & H PHARMACEUTICAL PVT LTD | cream · 20GM | ₹249 | 103% more |
| Metacortil LiteMacleods Pharmaceuticals Pvt Ltd | 15GM | ₹265 | 117% more |

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The information on Twinkle Star Oil is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.