Afung 200 mg Capsule

Afung 200 mg Capsule contains Fluconazole 200 mg (capsule). Prescription required.

Treatment of fungal infections such as vaginal candidiasis, oral/esophageal candidiasis (thrush), systemic candidiasis, cryptococcal meningitis, and other susceptible fungal infections as prescribed.

Fluconazole is a triazole antifungal that inhibits fungal cytochrome P450 enzyme (14-alpha-demethylase), blocking ergosterol synthesis. This disrupts the fungal cell membrane and inhibits growth/kills susceptible fungi.

Capsule for oral use. Take exactly as prescribed, usually once daily; may be taken with or without food. Swallow whole with water; take at the same time each day and complete the full course.

Nausea, abdominal pain, vomiting, diarrhea, headache, dizziness, rash, taste changes

Use with caution in liver disease (may cause hepatitis/raised liver enzymes); stop and seek care if severe rash, blistering, or signs of allergy occur. May cause QT prolongation/arrhythmias—caution in heart disease, electrolyte imbalance, or with QT-prolonging drugs. Dose adjustment may be needed in kidney impairment. Not effective for non-fungal infections; use only on medical advice.

Warfarin/other anticoagulants (increased bleeding risk), phenytoin, carbamazepine, cyclosporine, tacrolimus, sulfonylureas (hypoglycemia), rifampicin (reduced effect), zidovudine, theophylline, statins (e.g., simvastatin/atorvastatin), benzodiazepines (e.g., midazolam), QT-prolonging drugs (e.g., amiodarone, some antipsychotics/macrolides)

Store below 25°C in a cool, dry place; protect from moisture and direct light. Keep out of reach of children.

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