Agoprex

Agoprex contains Agomelatine (25mg) and is used for depression. Prescription required.

Depression

Agoprex Tablet is a melatonin agonist. It works by resynchronizing the sleep-wake cycle that is disturbed in depression.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Agoprex Tablet may be taken with or without food.

Nausea, Dry mouth, Drowsiness or difficulty sleeping, Headache, Weight change, Reduced sexual desire, Constipation

These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.

Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.

Store at room temperature (below 25°C), protected from light and moisture. Keep out of reach of children.