
Tablet · 2.5 mg · 10`S
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Tofacitinib 2.5 mg (as tofacitinib citrate)
Avozosin-T 2.5 mg Tablet contains Tofacitinib 2.5 mg (as tofacitinib citrate) and is used for autoimmune inflammatory conditions such as rheumatoid arthritis. Prescription required.
Monograph
Avozosin-T 2.5 mg Tablet is a prescription medicine containing Tofacitinib 2.5 mg (as tofacitinib citrate). It is used for autoimmune inflammatory conditions such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis (as prescribed by specialist) and may also be used for other immune-mediated diseases per doctor’s advice. It belongs to the group of medicines called Janus kinase (JAK) inhibitor.
Tablet for oral use. The dose and how long you take it depend on what you are being treated for and how you respond. Do not take more, or for longer, than your doctor has advised.
The side effects seen most often with Avozosin-T 2.5 mg Tablet are upper respiratory tract infection, headache, diarrhea and nausea. Most are mild and settle as the body gets used to the medicine. Tell your doctor if one persists or worries you.
Before you start, tell your doctor about any liver, kidney or heart problem, whether you are pregnant, planning a pregnancy or breastfeeding, and every other medicine you take, including supplements and ayurvedic preparations. Some of them can change how Avozosin-T 2.5 mg Tablet works.
Most side effects of Avozosin-T are mild and settle as the body gets used to the medicine. The ones reported most often are:
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Tablet for oral use. Take exactly as prescribed, at the same time each day, with or without food. Do not stop abruptly without medical advice; if you miss a dose, take it when remembered unless it is close to the next dose.
Tofacitinib is a Janus kinase (JAK) inhibitor. It blocks JAK1/JAK3 signaling pathways involved in cytokine activity, thereby reducing immune overactivity, inflammation, pain and tissue damage.
Prescription-only immunosuppressant. Increases risk of serious infections (TB, fungal, bacterial, viral); screening for TB/hepatitis may be required before and during therapy. Risk of herpes zoster, blood clots (DVT/PE), major cardiovascular events and certain malignancies may be increased in some patients; seek urgent care for chest pain, breathlessness, unilateral leg swelling, severe abdominal pain. Monitor CBC, liver function and lipids as advised; may cause low blood counts. Avoid live vaccines during treatment; keep vaccinations up to date prior to starting. Use caution in liver/kidney impairment; dose adjustments may be needed.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Strong CYP3A4 inhibitors (ketoconazole, clarithromycin), strong CYP3A4 inducers (rifampicin, carbamazepine, phenytoin), other immunosuppressants/biologics (azathioprine, cyclosporine, tacrolimus, TNF inhibitors), live vaccines
Store below 25°C in a cool, dry place away from light and moisture. Keep in original blister and out of reach of children.
Xeljanz 5 Tablet, Xeljanz XR 11 mg Tablet, Jaknat 5 Tablet, Tofajak 5 Tablet, Tofacitinib 5 mg Tablet (generic)
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
At a glance
Good to know
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance.
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