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JB CHEMICALS
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Important advisories specific to this medicine.
Pregnancy
Not recommended / Consult doctor (especially in 1st trimester; fluoroquinolones generally avoided in pregnancy)
Alcohol
Avoid (may cause flushing, nausea, vomiting, cramps with tinidazole)
Treatment of acute infectious diarrhoea and dysentery (including amoebic/bacterial mixed infections), gastroenteritis, and intestinal infections where both aerobic bacteria and anaerobic/protozoal organisms are suspected
Nausea, vomiting, abdominal pain, diarrhoea, metallic taste, headache, dizziness, loss of appetite
Ciprofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase/topoisomerase IV, stopping bacterial replication. Tinidazole is a nitroimidazole that forms reactive metabolites in anaerobic bacteria and protozoa, damaging DNA and leading to cell death.
Brand
JB CHEMICALS
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Manufacturer: JB CHEMICALS
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance.
Sources: Manufacturer labeling, CDSCO-approved drug information, established medical literature (standard pharmacology/ID guidelines)
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Treatment of acute infectious diarrhoea and dysentery (including amoebic/bacterial mixed infections), gastroenteritis, and intestinal infections where both aerobic bacteria and anaerobic/protozoal organisms are suspected
Ciprofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase/topoisomerase IV, stopping bacterial replication. Tinidazole is a nitroimidazole that forms reactive metabolites in anaerobic bacteria and protozoa, damaging DNA and leading to cell death.
Take by mouth as prescribed by a doctor. Usually taken after food with water; swallow whole. Complete the full course; avoid taking with milk/antacids/iron or zinc supplements within 2 hours before or 4–6 hours after ciprofloxacin.
Nausea, vomiting, abdominal pain, diarrhoea, metallic taste, headache, dizziness, loss of appetite
Prescription-only antibiotic; do not use for non-infectious diarrhoea. Fluoroquinolones may cause tendonitis/tendon rupture, peripheral neuropathy, CNS effects (seizures, confusion), and can worsen myasthenia gravis—seek medical help if pain/swelling in tendons or tingling/numbness occurs. Risk of QT prolongation and dysglycaemia in susceptible patients. Use caution in kidney/liver disease; dose adjustment may be needed. Tinidazole may cause dark urine and rarely blood count changes. Stop and seek care for severe diarrhoea, rash, jaundice, or allergic reaction. Avoid excessive sun exposure (photosensitivity risk with ciprofloxacin).
Alcohol (disulfiram-like reaction with tinidazole), antacids/sucralfate/iron/zinc/calcium supplements (reduce ciprofloxacin absorption), warfarin/acenocoumarol (increased bleeding risk), antiarrhythmics that prolong QT, theophylline, tizanidine (contraindicated with ciprofloxacin), antidiabetic drugs (hypo/hyperglycaemia), NSAIDs (seizure risk), corticosteroids (increased tendon rupture risk)
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Ciplox-TZ Tablet, Cifran TZ Tablet, Ciprobid TZ Tablet, Ciprin TZ Tablet, Cipro-TZ Tablet
Take by mouth as prescribed by a doctor. Usually taken after food with water; swallow whole. Complete the full course; avoid taking with milk/antacids/iron or zinc supplements within 2 hours before or 4–6 hours after ciprofloxacin.
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
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