Tablet · 15 Tablet
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Valproic Acid (58mg) + Sodium Valproate (135mg)
Epilex Chrono 200 Tablet contains Valproic Acid (58mg) + Sodium Valproate (135mg) and is used for epilepsy (generalized and focal seizures). Prescription required.
Before you take it
Not recommended
Epilex Chrono 200 Tablet CR is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Avoid
Do not drive or operate machinery while taking this medicine.
Epilex Chrono 200 Tablet CR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epilex Chrono 200 Tablet CR may not be needed in these patients. Please consult your doctor.<br>However, talk to your doctor if you have any underlying kidney disease.
Epilex Chrono 200 Tablet CR should be used with caution in patients with liver disease. Dose adjustment of Epilex Chrono 200 Tablet CR may be needed. Please consult your doctor.<br>Use of Epilex Chrono 200 Tablet CR is not recommended in patients with severe liver disease and active liver disease.
Monograph
Epilex Chrono 200 Tablet contains Valproic Acid (58mg) + Sodium Valproate (135mg) and is used for epilepsy (generalized and focal seizures). Prescription required.
Epilepsy (generalized and focal seizures), prevention of migraine (as prescribed), bipolar disorder/mania (as prescribed)
Controlled-release valproate increases brain GABA activity and reduces excessive neuronal firing. The chrono/CR formulation releases medicine gradually to maintain steadier blood levels.
Take with food at the same time each day. Swallow whole; do not crush or chew controlled-release tablets. Do not stop suddenly; follow your doctor’s titration schedule.
Nausea, indigestion, abdominal pain, diarrhea, increased appetite, weight gain, tremor, drowsiness, dizziness, hair loss
Risk of serious liver injury and pancreatitis; monitor for jaundice, severe abdominal pain, persistent vomiting. High risk in pregnancy (major birth defects and developmental delay); ensure effective contraception and specialist review. Monitor liver function tests and blood counts; caution with bleeding tendency. May cause sedation; avoid driving if affected.
Lamotrigine (higher levels and rash risk), carbamazepine, phenytoin, phenobarbital, topiramate (hyperammonemia), warfarin/anticoagulants (bleeding), aspirin (bleeding and increased valproate), alcohol and sedatives (increased drowsiness)
Store below 25°C, protected from light and moisture. Keep in original pack.
Epilex Chrono 300 Tablet
At a glance
Good to know
Brand
Abbott Healthcare Pvt Ltd
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Manufacturer
ABBOTT HEALTHCARE LIMITED
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: CDSCO, manufacturer labeling, established medical literature
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