Itzoft 200MG Caps 10S

Capsule

Treatment of fungal infections such as aspergillosis, candidiasis (including oral/oesophageal), cryptococcosis, dermatophytosis (tinea), pityriasis versicolor, and onychomycosis (fungal nail infection) as prescribed.

Itraconazole is a triazole antifungal that inhibits fungal CYP450 enzyme (14-α demethylase), blocking ergosterol synthesis. This disrupts fungal cell membrane formation and inhibits fungal growth.

Capsule for oral use. Take exactly as prescribed; typically taken with food/after a full meal for better absorption. Swallow whole; do not open/crush. Take at the same time daily and complete the full course.

Nausea, vomiting, abdominal pain, diarrhoea, headache, dizziness, rash, elevated liver enzymes

Prescription medicine. Can cause serious liver problems—seek help for jaundice, dark urine, severe fatigue, persistent nausea/vomiting. Contraindicated/avoid in patients with heart failure or history of congestive heart failure (negative inotropic effect). Many significant drug interactions via CYP3A4—review all medicines before use. Use caution in liver disease, kidney disease, and in elderly. Stop and seek care for severe allergic reactions or severe skin rash.

Strong CYP3A4 substrates with risk of serious reactions (e.g., simvastatin/lovastatin, certain antiarrhythmics like quinidine/dofetilide, ergot alkaloids, cisapride, some benzodiazepines like oral midazolam/triazolam); rifampicin/rifabutin, phenytoin, carbamazepine (reduce itraconazole levels); proton pump inhibitors/H2 blockers/antacids (reduce absorption—separate dosing if needed); warfarin (↑bleeding risk), digoxin (↑levels), cyclosporine/tacrolimus (↑levels), some calcium channel blockers (↑levels/edema), certain HIV drugs (dose adjustments).

Store below 25°C, protected from moisture and light. Keep in original blister pack and out of reach of children.

Sporanox 200 Capsule, Canditral 200 Capsule, Itrasys 200 Capsule, Itaspor 200 Capsule, Itracon 200 Capsule