OZORON DSR CAP

Distributor inventory | Capsule

Gastroesophageal reflux disease (GERD), acidity/heartburn, gastritis, peptic ulcer disease, nausea and vomiting associated with acid reflux or delayed gastric emptying

Rabeprazole is a proton pump inhibitor that reduces stomach acid by blocking the H+/K+ ATPase pump in gastric parietal cells. Domperidone is a prokinetic/antiemetic that blocks dopamine (D2) receptors in the gut, improving gastric motility and reducing nausea and reflux symptoms.

Take by mouth as directed by a doctor, usually 1 capsule once daily 15–30 minutes before food (preferably before breakfast). Swallow whole; do not crush or chew (enteric-coated/SR formulation).

Headache, diarrhea, abdominal pain, nausea, constipation, dry mouth, dizziness, flatulence

Use with caution in liver disease; dose adjustment/monitoring may be needed. Domperidone may increase risk of QT prolongation/serious arrhythmias—avoid in patients with known QT prolongation, significant electrolyte disturbances, or moderate/severe hepatic impairment; do not exceed prescribed dose. Long-term PPI use may be associated with low magnesium/vitamin B12, fractures, and C. difficile-associated diarrhea; use the lowest effective dose. Seek medical advice if alarm symptoms occur (blood in vomit/stool, unexplained weight loss, persistent vomiting, difficulty swallowing).

QT-prolonging drugs (e.g., amiodarone, sotalol, certain antipsychotics), strong CYP3A4 inhibitors (e.g., ketoconazole/itraconazole, clarithromycin, erythromycin, ritonavir) increase domperidone levels and arrhythmia risk; other PPIs/antacids (timing considerations), warfarin (monitor INR), digoxin, methotrexate (high-dose), drugs needing acidic pH for absorption (e.g., ketoconazole, atazanavir, erlotinib)

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

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